Photo of Peter Mayinger, Ph.D.

Peter Mayinger Ph.D.

    • Associate Professor of Medicine, Division of Nephrology and Hypertension School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Dr. Mayinger's research focuses on mermbranes and sorting, cell signaling, cell proliferation and differentiation, lipid signaling disorders, and cell proliferative diseases.

Education

  • B.S., Technical University, Munich Germany 1986
  • Ph.D., Ludwig Maximilans University, Munich Germany 1992
  • Ph.D., Heidelberg University, Heidelberg Germany 2001
  • Fellowship:

    • Biological Chemistry - UCLA, 1992-1995

Memberships and associations

  • American Society of Nephrology

Publications

  • "Delayed turnover of unphosphorylated Ssk1 during carbon stress activates the yeast Hog1 MAP kinase pathway." PLoS One  In: , Vol. 10, No. 9, e0137199, 04.09.2015.
  • "Phosphoregulatory protein 14-3-3 facilitates SAC1 transport from the endoplasmic reticulum." Proceedings of the National Academy of Sciences of the United States of America  In: , Vol. 112, No. 25, 23.06.2015, p. E3199-E3206.
  • "The First Transmembrane Domain of Lipid Phosphatase SAC1 Promotes Golgi Localization." PLoS One  In: , Vol. 8, No. 8, e71112, 01.08.2013.
  • "Metabolic Activation of the HOG MAP Kinase Pathway by Snf1/AMPK Regulates Lipid Signaling at the Golgi." Traffic  In: , Vol. 13, No. 11, 11.2012, p. 1522-1531.
  • "Phosphoinositides and vesicular membrane traffic." Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids  In: , Vol. 1821, No. 8, 08.2012, p. 1104-1113.
  • "Growth and metabolic control of lipid signalling at the Golgi." Biochemical Society Transactions  In: , Vol. 40, No. 1, 02.2012, p. 205-209.
  • "Signaling at the Golgi." Cold Spring Harbor perspectives in biology  In: , Vol. 3, No. 5, 05.2011, p. 1-14.
  • "Spatial regulation of golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity." Traffic  In: , Vol. 11, No. 9, 09.2010, p. 1180-1190.
  • "Regulation of Golgi function via phosphoinositide lipids." Seminars in Cell and Developmental Biology  In: , Vol. 20, No. 7, 09.2009, p. 793-800.
  • "SAC1 lipid phosphatase and growth control of the secretory pathway." Molecular BioSystems  In: , Vol. 5, No. 1, 2009, p. 36-42.
  • "Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1." Journal of Cell Biology  In: , Vol. 180, No. 4, 25.02.2008, p. 803-812.
  • "Expression of yeast lipid phosphatase Sac1p is regulated by phosphatidylinositol-4-phosphate." BMC Molecular Biology  In: , Vol. 9, 16, 28.01.2008.
  • "Growth control of golgi phosphoinositides by reciprocal localization of sac1 lipid phosphatase and pik1 4-kinase." Traffic  In: , Vol. 8, No. 11, 11.2007, p. 1554-1567.
  • "Inactivation of the phosphoinositide phosphatases Sac1p and Inp54p leads to accumulation of phosphatidylinositol 4,5-bisphosphate on vacuole membranes and vacuolar fusion defects." Journal of Biological Chemistry In: , Vol. 282, No. 22, 01.06.2007, p. 16295-16307.
  • "Analysis of phosphoinositide-binding proteins using liposomes as an affinity matrix." BioTechniques  In: , Vol. 38, No. 6, 06.2005, p. 858-862.
  • "Regulation of intracellular phosphatidylinositol-4-phosphate by the Sac1 lipid phosphatase." Traffic  In: , Vol. 6, No. 2, 02.2005, p. 116-130.
  • "Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p." Journal of Cell Biology  In: , Vol. 168, No. 2, 17.01.2005, p. 185-191.
  • "The Human Phosphatidylinositol Phosphatase SAC1 Interacts with the Coatomer I Complex." Journal of Biological Chemistry  In: , Vol. 278, No. 52, 26.12.2003, p. 52689-52699.
  • "Role for lipid signaling and the cell integrity MAP kinase cascade in yeast septum biogenesis." Current Genetics  In: , Vol. 43, No. 2, 01.05.2003, p. 71-78.
  • "Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport." Journal of Biological Chemistry  In: , Vol. 277, No. 12, 22.03.2002, p. 10547-10554.
  • "The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase." Current Biology  In: , Vol. 11, No. 18, 18.09.2001, p. 1421-1426.
  • "Reconstitution of yeast microsomal lipid flip-flop using endogenous aminophospholipids." FEBS Letters  In: , Vol. 476, No. 3, 07.07.2000, p. 277-281.
  • "Sac1p plays a crucial role in microsomal ATP transport, which is distinct from its function in Golgi phospholipid metabolism." EMBO Journal  In: , Vol. 18, No. 6, 15.03.1999, p. 1506-1515.
  • "Essential role for diacylglycerol in protein transport from the yeast Golgi complex." Nature In: , Vol. 387, No. 6628, 01.05.1997, p. 101-105.
  • "Sac1p mediates the adenosine triphosphate transport into yeast endoplasmic reticulum that is required for protein translocation." Journal of Cell Biology In: , Vol. 131, No. 6 I, 12.1995, p. 1377-1386.
  • "Effects of ATP on ligand recognition of platelet fibrinogen receptor on GPIIb-IIIa." American Journal of Physiology - Heart and Circulatory Physiology In: , Vol. 267, No. 3 36-3, 1994.
  • "An ATP transporter is required for protein translocation into the yeast endoplasmic reticulum." EMBO Journal  In: , Vol. 12, No. 2, 1993, p. 659-666.
  • "Photoaffinity labeling of integrin αIIbβ3 (glycoprotein IIb-IIIa) on intact platelets with 8-azido-[γ-32P]ATP." BBA - Molecular Cell Research  In: , Vol. 1137, No. 1, 06.10.1992, p. 77-81.
  • "Labeling of two different regions of the nucleotide binding site of the uncoupling protein from brown adipose tissue mitochondria with two ATP analogs." Biochemistry  In: , Vol. 31, No. 43, 1992, p. 10536-10543.
  • "Photoaffinity labeling of dog pancreas microsomes with 8-azido-ATP inhibits association of nascent preprolactin with the signal sequence receptor complex." FEBS Letters  In: , Vol. 286, No. 1-2, 29.07.1991, p. 95-99.

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