Photo of Lisa Coussens, Ph.D.

Lisa Coussens Ph.D.

  • (503) 494-9336
    • Professor of Cell, Developmental and Cancer Biology School of Medicine
    • Hildegard Lamfrom Chair of Basic Science
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Cancer Biology Graduate Program School of Medicine

Publications

  • "Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis." Cell Reports In: , Vol. 19, No. 1, 04.04.2017, p. 203-217.
  • "Colorectal Cancer Liver Metastasis : Evolving Paradigms and Future Directions." CMGH Cellular and Molecular Gastroenterology and Hepatology In: , Vol. 3, No. 2, 01.03.2017, p. 163-173.
  • "Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis." Journal of Investigative Dermatology  In: , Vol. 137, No. 2, 01.02.2017, p. 359-366.
  • "MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment." Nature Communications  In: , Vol. 7, 13597, 25.11.2016.
  • "Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues." Nature Nanotechnology  In: , Vol. 11, No. 11, 01.11.2016, p. 986-994.
  • "The Basis of Oncoimmunology." Cell In: , Vol. 164, No. 6, 10.03.2016, p. 1233-1247.
  • "Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma." OncoImmunology In: , Vol. 5, No. 3, 03.03.2016.
  • "Bruton tyrosine kinase–Dependent immune cell cross-talk drives pancreas cancer." Cancer Discovery In: , Vol. 6, No. 3, 01.03.2016, p. 270-285.
  • "Erratum : Sustained endothelial expression of HoxA5 in vivo impairs pathological angiogenesis and tumor progression (PLoS ONE (2015) 10: 3 (E0121720) DOI: 10.1371/journal.pone.0121720)." PLoS One  In: , Vol. 11, No. 2, e0148833, 01.02.2016.
  • "Lymphatic vessels, inflammation, and immunity in skin cancer." Cancer Discovery In: , Vol. 6, No. 1, 01.01.2016, p. 22-35.
  • "Senescence and cancer : An evolving inflammatory paradox." Biochimica et Biophysica Acta - Reviews on Cancer In: , Vol. 1865, No. 1, 01.01.2016, p. 14-22.
  • "Immune Response to Cancer Therapy : Mounting an Effective Antitumor Response and Mechanisms of Resistance." Trends in Cancer In: , Vol. 1, No. 1, 01.09.2015, p. 66-75.
  • "Myeloid Cells as Targets for Therapy in Solid Tumors." Cancer Journal (United States) In: , Vol. 21, No. 4, 05.07.2015, p. 343-350.
  • "T2-polarized CD4 T Cells and macrophages limit efficacy of radiotherapy." Cancer immunology research In: , Vol. 3, No. 5, 01.05.2015, p. 518-525.
  • "Macrophages and therapeutic resistance in cancer." Cancer Cell In: , Vol. 27, No. 4, 13.04.2015, p. 462-472.
  • "Sustained endothelial expression of HoxA5 in vivo impairs pathological angiogenesis and tumor progression." PLoS One  In: , Vol. 10, No. 3, e0121720, 30.03.2015.
  • "Macrophage IL-10 Blocks CD8+ T Cell-Dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells." Cancer Cell In: , Vol. 26, No. 5, 10.11.2014, p. 623-637.
  • "Manipulating MicroRNAs to regulate macrophage polarization in gliomas." Journal of the National Cancer Institute In: , Vol. 106, No. 8, dju230, 01.08.2014.
  • "B cells regulate macrophage phenotype and response to chemotherapy in squamous carcinomas." Cancer Cell In: , Vol. 25, No. 6, 16.06.2014, p. 809-821.
  • "Duality of the immune response in cancer : lessons learned from skin." The Journal of investigative dermatology In: , Vol. 134, No. e1, 2014, p. E23-E28.
  • "Manipulating microRNAs to regulate macrophage polarization in gliomas." Journal of the National Cancer Institute In: , Vol. 106, No. 8, 2014.
  • "Classification of current anticancer immunotherapies." Oncotarget  In: , Vol. 5, No. 24, 2014, p. 12472-12508.
  • "A listeria vaccine and depletion of t-regulatory cells activate immunity against early stage pancreatic intraepithelial neoplasms and prolong survival of mice." Gastroenterology In: , Vol. 146, No. 7, 2014.
  • "Mammary gland involution as an immunotherapeutic target for postpartum breast cancer." Journal of Mammary Gland Biology and Neoplasia  In: , Vol. 19, No. 2, 2014, p. 213-228.
  • "Poker face no more : cancer recurrence reveals its hand." Nature Medicine In: , Vol. 19, No. 12, 12.2013, p. 1569-1570.
  • "Dendritic cells, inflammation, and breast cancer." Cancer Journal (United States)  In: , Vol. 19, No. 6, 11.2013, p. 511-516.
  • "Cathepsin C is a tissue-specific regulator of squamous carcinogenesis." Genes and Development In: , Vol. 27, No. 19, 01.10.2013, p. 2086-2098.
  • "Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma." Journal of Immunology In: , Vol. 191, No. 4, 15.08.2013, p. 2009-2017.
  • "B cells and their mediators as targets for therapy in solid tumors." Experimental Cell Research In: , Vol. 319, No. 11, 01.07.2013, p. 1644-1649.
  • "Some dcs are "b"etter." Immunity  In: , Vol. 38, No. 4, 18.04.2013, p. 626-628.

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