Photo of Laurence Trussell, Ph.D.

Laurence Trussell Ph.D.

  •      (503) 494-3424
    • Professor of Otolaryngology - Head and Neck Surgery School of Medicine
    • Joint Appointment Vollum Institute
    • Neuroscience Graduate Program School of Medicine
    • Physiology and Pharmacology Graduate Program School of Medicine

Laurence Trussell received his Ph.D. in Biology from the University of California, Los Angeles in 1983. After initial postdoctoral work at UCLA, he obtained further training at Washington University, St. Louis. In 1990, he received a faculty appointment at the University of Wisconsin, Madison. In 1999, he was appointed as professor in the Oregon Hearing Research Center with an appointment as scientist at the Vollum Institute.

These are a few of Dr. Trussell's major milestones and significant discoveries:
- Neurons that encode timing of acoustic signals are molecularly and biophysically specialized for that function
- Cellular/synaptic learning mechanisms occur even at the earliest levels of sensory processing
- Co-release of multiple transmitters from neurons act together on the same receptor
- Ca2+ channels are expressed in axons and control the triggering of complex spike activity

Areas of interest

  • Brainstem circuits that process acoustic signals
  • Synaptic physiology: How do cells and synapses preserve information provided by the ear?

Education

  • Ph.D., University of California, Los Angeles 1983

Publications

  • Lu HW and Trussell LO. (2016) Spontaneous activity defines effective convergence ratios in an inhibitory circuit. J. Neurosci. 36:3268-3280.

  • Yaeger DB and Trussell LO. (2015) Single granule cells excite Golgi cells and evoke feedback inhibition in the cochlear nucleus. J. Neurosci. 35:4741-4750.

  • Tang ZQ and Trussell LO. (2015) Serotonergic regulation of excitability of principal cells of the dorsal cochlear nucleus. J. Neurosci. 35:4540-4551.

  • Borges-Merjane C and Trussell LO. (2015) ON and OFF unipolar brush cells transform multisensory inputs to the auditory system. Neuron 85:1029-1042.

  • Huang H and Trussell LO. (2014) Presynaptic HCN channels regulate vesicular glutamate transport. Neuron 84:340-346.

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