After earning his B.S. in Neuroscience from Allegheny College in 2001, Kevin Wright received his Ph.D. in Neurobiology from The University of North Carolina, Chapel Hill in 2006. He did his postdoctoral training at Johns Hopkins Medical Institute. In 2013, he was appointed as an assistant scientist at the Vollum Institute.
The Wright Lab uses genetic, molecular, and biochemical approaches to identify the specific molecular pathways that allow genetically distinct subtypes of neurons to respond differentially to cues within the extracellular environment to form a functional neural circuit. The goal is to develop a better understanding of how axon guidance, laminar targeting, dendritic arborization and synaptogenesis occur throughout the developing nervous system, and how they are disrupted in neurodevelopmental disorders.
Areas of interest
- axon guidance
- neuronal migration
- neural circuitry
- Ph.D., University of North Carolina, Chapel Hill 2006
- B.S., Allegheny College 2001
Charoy C, Nawabi H, Reynaud F, Derrington E, Bozon M, Wright K, Falk J, Helmbacher F, Kindbeiter K, Castellani V. (2012) GDNF activates midline repulsion by Semaphorin3B via NCAM during commissural axon guidance. Neuron 75:1051-1066.
Wright KM, Lyon K, Leung H, Leahy DJ, Ma L, Ginty DD (2012) Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron 76:931-944.
Willer T, Inamori KI, Venzke D, Harvey C, Morgensen G, Hara Y, Beltrán Valero de Bernabé D, Yu L, Wright KM, Campbell KP. (2014) The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation. eLife 3:e03941.
Clements R, Turk R, Campbell KP, Wright KM. (2017) Dystroglycan maintains inner limiting membrane integrity to coordinate retinal development. J Neurosci 37:8559-8574.