Photo of Joseph F. Quinn, M.D.

Joseph F. Quinn M.D.

    • Professor of Neurology School of Medicine
    • Director OHSU Parkinson's Disease and Movement Disorder Program School of Medicine
    • Neuroscience Graduate Program School of Medicine

Director of the OHSU Parkinson Center and Movement Disorder Program

Director of the Portland VAMC Parkinson’s Disease Research, Education, and Clinical Center (PADRECC)

Professor of Neurology, OHSU School of Medicine

Dr. Quinn is NIH and VA-funded to conduct translational research in neurodegenerative disease, including work with animal models, biomarkers, and clinical trials. His research focus is on cognitive decline in Parkinson’s disease and other neurodegenerative diseases.

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  • Residency:

    • Neurology-Oregon Health & Science University, Portland
  • Fellowship:

    • Geriatric neurology-VAMC Portland

Publications

  • "Centella asiatica attenuates Aβ-induced neurodegenerative spine loss and dendritic simplification." Neuroscience Letters  In: , Vol. 646, 12.04.2017, p. 24-29.
  • "Mass-Spectrometry-Based Method to Quantify in Parallel Tau and Amyloid β 1-42 in CSF for the Diagnosis of Alzheimer's Disease." Journal of Proteome Research  In: , Vol. 16, No. 3, 03.03.2017, p. 1228-1238.
  • "Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease." Scientific Reports  In: , Vol. 7, 39880, 12.01.2017.
  • "Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies : a retrospective analysis." The Lancet Neurology In: , Vol. 16, No. 1, 01.01.2017, p. 1234.
  • "Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains." JAMA Neurology In: , Vol. 74, No. 1, 01.01.2017, p. 91-99.
  • "MicroRNAs in human cerebrospinal fluid as biomarkers for Alzheimer's disease." Journal of Alzheimer's Disease In: , Vol. 55, No. 3, 2017, p. 1223-1233.
  • "CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease." Alzheimer's and Dementia  In: , Vol. 12, No. 11, 01.11.2016, p. 1125-1131.
  • "Do ϵ-3 fatty acids regulate cerebral β amyloid?" JAMA Neurology In: , Vol. 73, No. 10, 01.10.2016, p. 1183-1184.
  • "Association of GBA mutations and the E326K polymorphism with motor and cognitive progression in parkinson disease." JAMA Neurology In: , Vol. 73, No. 10, 01.10.2016, p. 1217-1224.
  • "The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer's disease." Alzheimer's Research and Therapy In: , Vol. 8, No. 1, 25, 30.06.2016.
  • "Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis." Nature Communications In: , Vol. 7, 11934, 21.06.2016.
  • "Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults." JAMA Neurology  In: , Vol. 73, No. 6, 01.06.2016, p. 721-732.
  • "Comment : Gene-environment interactions in dementia -: Not just another fish story." Neurology  In: , Vol. 86, No. 22, 31.05.2016, p. 2069.
  • "Assessment of the genetic variance of late-onset Alzheimer's disease." Neurobiology of Aging  In: , Vol. 41, 01.05.2016, p. 200.e13-200.e20.
  • "STX, a novel membrane estrogen receptor ligand, protects against amyloid-β toxicity." Journal of Alzheimer's Disease In: , Vol. 51, No. 2, 15.03.2016, p. 391-403.
  • "Centella asiatica modulates antioxidant and mitochondrial pathways and improves cognitive function in mice." Journal of Ethnopharmacology  In: , Vol. 180, 02.03.2016, p. 78-86.
  • "Precision medicine : Clarity for the complexity of dementia." American Journal of Pathology In: , Vol. 186, No. 3, 01.03.2016, p. 500-506.
  • "Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci." PLoS One  In: , Vol. 11, No. 2, e0148717, 01.02.2016.
  • "GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease." Movement Disorders In: , Vol. 31, No. 1, 01.01.2016, p. 95-102.
  • "Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples : Mendelian randomization analyses." Alzheimer's and Dementia  In: , Vol. 11, No. 12, 01.12.2015, p. 1439-1451.
  • "Association of long runs of homozygosity with Alzheimer disease among African American individuals." JAMA Neurology  In: , Vol. 72, No. 11, 01.11.2015, p. 1313-1323.
  • "Targeted Lipidomics of Fontal Cortex and Plasma Diacylglycerols (DAG) in Mild Cognitive Impairment and Alzheimer's Disease : Validation of DAG Accumulation Early in the Pathophysiology of Alzheimer's Disease." Journal of Alzheimer's Disease In: , Vol. 48, No. 2, 09.09.2015, p. 537-546.
  • "Increased CSF E-selectin in clinical Alzheimer's disease without altered CSF Aβ and tau." Journal of Alzheimer's Disease  In: , Vol. 47, No. 4, 11.08.2015, p. 883-887.
  • "Association of cognitive domains with postural instability/gait disturbance in Parkinson's disease." Parkinsonism and Related Disorders In: , Vol. 21, No. 7, 01.07.2015, p. 692-697.
  • "Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE." Nature Communications In: , Vol. 6, 6760, 19.05.2015.
  • "Cognitive profile of LRRK2-related Parkinson's disease." Movement Disorders In: , Vol. 30, No. 5, 15.04.2015, p. 728-733.
  • "Alterations in mitochondrial number and function in Alzheimer’s disease fibroblasts." Metabolic Brain Disease In: , Vol. 30, No. 5, 12.04.2015, p. 1275-1278.
  • "Non-targeted lipidomics of CSF and frontal cortex grey and white matter in control, mild cognitive impairment, and Alzheimer's disease subjects." Acta Neuropsychiatrica In: , Vol. 27, No. 5, 16.03.2015, p. 270-278.
  • "Cerebrospinal fluid peptides as potential parkinson disease biomarkers : A staged pipeline for discovery and validation." Molecular and Cellular Proteomics  In: , Vol. 14, No. 3, 01.03.2015, p. 544-555.
  • "Rarity of the alzheimer disease-protective APP A673T variant in the United States." JAMA Neurology In: , Vol. 72, No. 2, 01.02.2015, p. 209-216.

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