Photo of Joseph F. Quinn, M.D.

Joseph F. Quinn M.D.

    • Professor of Neurology School of Medicine
    • Director OHSU Parkinson Center and Movement Disorders Program School of Medicine
    • Director, Portland VAMC Parkinson’s Disease Research, Education, and Clinical Center (PADRECC)
    • Neuroscience Graduate Program School of Medicine

Director of the OHSU Parkinson Center and Movement Disorder Program

Director of the Portland VAMC Parkinson’s Disease Research, Education, and Clinical Center (PADRECC)

Professor of Neurology, OHSU School of Medicine

Dr. Quinn is NIH and VA-funded to conduct translational research in neurodegenerative disease, including work with animal models, biomarkers, and clinical trials. His research focus is on cognitive decline in Parkinson’s disease and other neurodegenerative diseases.

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  • Residency:

    • Neurology-Oregon Health & Science University, Portland
  • Fellowship:

    • Geriatric neurology-VAMC Portland

Publications

  • "Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features." Scientific Reports  In: , Vol. 7, No. 1, 8137, 01.12.2017.
  • "Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty." Scientific Reports  In: , Vol. 7, No. 1, 14052, 01.12.2017.
  • "Centella asiatica : phytochemistry and mechanisms of neuroprotection and cognitive enhancement." Phytochemistry Reviews  In: , 20.09.2017, p. 1-34.
  • "The effects of noncoding aquaporin-4 single-nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease." Alzheimer's and Dementia: Translational Research and Clinical Interventions In: , Vol. 3, No. 3, 01.09.2017, p. 348-359.
  • "Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease." Nature Genetics In: , Vol. 49, No. 9, 01.09.2017, p. 1373-1384.
  • "Large-scale exploratory genetic analysis of cognitive impairment in Parkinson's disease." Neurobiology of Aging In: , Vol. 56, 01.08.2017, p. 211.e1-211.e7.
  • "Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults." Alzheimer's Research and Therapy In: , Vol. 9, No. 1, 48, 03.07.2017.
  • "An alpha-synuclein MRM assay with diagnostic potential for Parkinson's disease and monitoring disease progression." Proteomics - Clinical Applications  In: , Vol. 11, No. 7-8, 1700045, 01.07.2017.
  • "Transethnic genome-wide scan identifies novel Alzheimer's disease loci." Alzheimer's and Dementia  In: , Vol. 13, No. 7, 01.07.2017, p. 727-738.
  • "Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease." JAMA Neurology  In: , Vol. 74, No. 5, 01.05.2017, p. 557-566.
  • "Centella asiatica attenuates Aβ-induced neurodegenerative spine loss and dendritic simplification." Neuroscience Letters  In: , Vol. 646, 12.04.2017, p. 24-29.
  • "Mass-Spectrometry-Based Method to Quantify in Parallel Tau and Amyloid β 1-42 in CSF for the Diagnosis of Alzheimer's Disease." Journal of Proteome Research  In: , Vol. 16, No. 3, 03.03.2017, p. 1228-1238.
  • "Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease." Scientific Reports  In: , Vol. 7, 39880, 12.01.2017.
  • "Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies : a retrospective analysis." The Lancet Neurology In: , Vol. 16, No. 1, 01.01.2017, p. 1234.
  • "Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains." JAMA Neurology In: , Vol. 74, No. 1, 01.01.2017, p. 91-99.
  • "Common variant rs356182 near SNCA defines a Parkinson's disease endophenotype." Annals of Clinical and Translational Neurology In: , Vol. 4, No. 1, 01.01.2017, p. 15-25.
  • "MicroRNAs in human cerebrospinal fluid as biomarkers for Alzheimer's disease." Journal of Alzheimer's Disease In: , Vol. 55, No. 3, 2017, p. 1223-1233.
  • "Serum hepcidin levels, iron dyshomeostasis and cognitive loss in Alzheimer'S Disease." Aging and Disease  In: , Vol. 8, No. 2, 2017, p. 215-227.
  • "Prediction of Conversion to Alzheimer's Disease with Longitudinal Measures and Time-To-Event Data." Journal of Alzheimer's Disease  In: , Vol. 58, No. 2, 2017, p. 361-371.
  • "Homocysteine and cognitive function in Parkinson's disease." Parkinsonism and Related Disorders In: , 2017.
  • "Centella asiatica Attenuates Mitochondrial Dysfunction and Oxidative Stress in Aβ-Exposed Hippocampal Neurons." Oxidative Medicine and Cellular Longevity  In: , Vol. 2017, 7023091, 2017.
  • "CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease." Alzheimer's and Dementia  In: , Vol. 12, No. 11, 01.11.2016, p. 1125-1131.
  • "Do ϵ-3 fatty acids regulate cerebral β amyloid?" JAMA Neurology In: , Vol. 73, No. 10, 01.10.2016, p. 1183-1184.
  • "Association of GBA mutations and the E326K polymorphism with motor and cognitive progression in parkinson disease." JAMA Neurology In: , Vol. 73, No. 10, 01.10.2016, p. 1217-1224.
  • "The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer's disease." Alzheimer's Research and Therapy In: , Vol. 8, No. 1, 25, 30.06.2016.
  • "Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis." Nature Communications In: , Vol. 7, 11934, 21.06.2016.
  • "Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults." JAMA Neurology  In: , Vol. 73, No. 6, 01.06.2016, p. 721-732.
  • "Comment : Gene-environment interactions in dementia -: Not just another fish story." Neurology  In: , Vol. 86, No. 22, 31.05.2016, p. 2069.
  • "Assessment of the genetic variance of late-onset Alzheimer's disease." Neurobiology of Aging  In: , Vol. 41, 01.05.2016, p. 200.e13-200.e20.
  • "STX, a novel membrane estrogen receptor ligand, protects against amyloid-β toxicity." Journal of Alzheimer's Disease In: , Vol. 51, No. 2, 15.03.2016, p. 391-403.

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