Photo of Jonathan Q. Purnell, M.D.

Jonathan Q. Purnell M.D.

  • (503) 494-1775
    • Professor of Medicine, Division of Cardiovascular Medicine School of Medicine
    • Graduate Programs in Human Nutrition School of Medicine

Dr. Purnell’s clinical interests include endocrinology, metabolism, obesity, diabetes and hyperlipidema. He received his medical degree from OHSU in 1986, and completed his residency training at the University of Vermont in Burlington. He completed his endocrinology fellowship at the University of Washington in Seattle. Dr. Purnell is board certified in internal medicine and in endocrinology.

Education

  • M.D., Oregon Health & Science University, Portland Oregon 1986
  • Residency:

    • University of Vermont, Burlington, Vermont
  • Fellowship:

    • Endocrinology-University of Washington, Seattle

Memberships and associations

  • Internal medicine, 1989

Publications

  • "Contraception and Conception After Bariatric Surgery." Obstetrics and gynecology In: , Vol. 130, No. 5, 01.11.2017, p. 979-987.
  • "Maternal pregravid obesity remodels the DNA methylation landscape of cord blood monocytes disrupting their inflammatory program." Journal of Immunology  In: , Vol. 199, No. 8, 15.10.2017, p. 2729-2744.
  • "Application of PCSK9 inhibitors in practice : Challenges and opportunities." Circulation Research In: , Vol. 121, No. 5, 01.08.2017, p. 499-501.
  • "Thyroid function variation in the normal range, energy expenditure, and body composition in l-t4-treated subjects." Journal of Clinical Endocrinology and Metabolism In: , Vol. 102, No. 7, 01.07.2017, p. 2533-2542.
  • "Poorer maternal diet quality and increased birth weight ." Journal of Maternal-Fetal and Neonatal Medicine In: , 17.05.2017, p. 1-7.
  • "Discordant response of low-density lipoprotein cholesterol and lipoprotein(a) levels to monoclonal antibodies targeting proprotein convertase subtilisin/kexin type 9." Journal of Clinical Lipidology In: , 13.01.2017.
  • "Glycemic Control and Urinary Tract Infections in Women with Type 1 Diabetes : Results from the DCCT/EDIC." Journal of Urology  In: , Vol. 196, No. 4, 01.10.2016, p. 1129-1135.
  • "Type 2 diabetes remission rates after laparoscopic gastric bypass and gastric banding : Results of the longitudinal assessment of bariatric surgery study." Diabetes Care In: , Vol. 39, No. 7, 01.07.2016, p. 22-28.
  • "Significance of epicardial and intrathoracic adipose tissue volume among type 1 diabetes patients in the DCCT/EDIC : A pilot study." PLoS One  In: , Vol. 11, No. 7, e0159958, 01.07.2016.
  • "Comparison of multiple methods to measure maternal fat mass in late gestation." American Journal of Clinical Nutrition In: , Vol. 103, No. 4, 01.04.2016, p. 1055-1063.
  • "Effects of levothyroxine replacement or suppressive therapy on energy expenditure and body composition." Thyroid In: , Vol. 26, No. 3, 01.03.2016, p. 347-355.
  • "Macronutrient regulation of ghrelin and peptide YY in pediatric obesity and prader-willi syndrome." Journal of Clinical Endocrinology and Metabolism In: , Vol. 100, No. 10, 01.10.2015, p. 3822-3831.
  • "Maternal obesity alters immune cell frequencies and responses in umbilical cord blood samples." Pediatric Allergy and Immunology  In: , Vol. 26, No. 4, 01.06.2015, p. 344-351.
  • "Loss of pons-to-hypothalamic white matter tracks in brainstem obesity." International Journal of Obesity In: , Vol. 38, No. 12, 11.12.2014, p. 1573-1577.
  • "Short-term, low-dose GH therapy improves insulin sensitivity without modifying cortisol metabolism and ectopic fat accumulation in adults with GH deficiency." Journal of Clinical Endocrinology and Metabolism In: , Vol. 99, No. 10, 01.10.2014, p. E1862-E1869.
  • "Metabolic syndrome prevalence and associations in a bariatric surgery cohort from the longitudinal assessment of bariatric surgery-2 study." Metabolic Syndrome and Related Disorders In: , Vol. 12, No. 2, 01.03.2014, p. 86-94.
  • "Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops." Molecular Nutrition and Food Research In: , Vol. 58, No. 2, 02.2014, p. 248-255.
  • "Expectancy, Self-Efficacy, and Placebo Effect of a Sham Supplement for Weight Loss in Obese Adults." Journal of Evidence-Based Complementary and Alternative Medicine  In: , Vol. 19, No. 3, 2014, p. 181-188.
  • "Altered body composition and energy expenditure but normal glucose tolerance among humans with a long-chain fatty acid oxidation disorder." American Journal of Physiology - Endocrinology and Metabolism In: , Vol. 305, No. 10, 15.11.2013.
  • "Intrahepatic lipid, not visceral or muscle fat, is correlated with insulin resistance in older, female rhesus macaques." Obesity In: , Vol. 21, No. 10, 10.2013, p. 2021-2028.
  • "Improvement in insulin sensitivity during mifepristone treatment of cushing syndrome : Early and late effects." Diabetes Care In: , Vol. 36, No. 9, 09.2013.
  • "Change in postprandial substrate oxidation after a high-fructose meal is related to body mass index in healthy men." Nutrition Research In: , Vol. 33, No. 6, 06.2013, p. 435-441.
  • "Effects of a high-protein diet on regulation of phosphorus homeostasis." Journal of Clinical Endocrinology and Metabolism In: , Vol. 98, No. 3, 03.2013, p. 1207-1213.
  • "Omentectomy added to Roux-en-Y gastric bypass surgery : A randomized, controlled trial." Surgery for Obesity and Related Diseases In: , Vol. 9, No. 2, 03.2013, p. 269-275.
  • "Postprandial total ghrelin suppression is modulated by melanocortin signaling in humans." Journal of Clinical Endocrinology and Metabolism  In: , Vol. 98, No. 2, 02.2013.
  • "The effect of excess weight gain with intensive diabetes mellitus treatment on cardiovascular disease risk factors and atherosclerosis in type 1 diabetes mellitus : Results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC) study." Circulation In: , Vol. 127, No. 2, 15.01.2013, p. 180-187.
  • "Fructose ingestion and cerebral, metabolic, and satiety responses." JAMA - Journal of the American Medical Association In: , Vol. 309, No. 1, 02.01.2013, p. 85-86.
  • "Treating diabetes with surgery." JAMA - Journal of the American Medical Association In: , Vol. 309, No. 21, 2013, p. 2274-2275.
  • "Comparison of 3 T MRI and CT for the measurement of visceral and subcutaneous adipose tissue in humans." British Journal of Radiology In: , Vol. 85, No. 1018, 10.2012.
  • "Energizing the mind and body." Diabetes In: , Vol. 61, No. 9, 09.2012, p. 2216-2218.

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