Photo of Hiroko H. Dodge, Ph.D.

Hiroko H. Dodge Ph.D.

    • Associate Professor of Neurology School of Medicine

In addition to her statistical expertise, her research interests cover a wide range of areas, including epidemiology of dementia, cross cultural comparisons on healthy aging between Okinawa, Japan and Oregon, collaborating with the Okinawa Centenarian Study project, application of demographic methods to clinical research, longitudinal data analyses and clinical trial methods. She recently created a Professional Interest Area (PIA) entitled "Clinical Trials Advancements and Outcomes" in the International Society to Advance Alzheimer's Research (ISTAART, an international AD research organization sponsored by the Alzheimer's Association). This PIA creates an international researchers' forum where innovative clinical trial approaches, developments of outcomes sensitive to trial effects, and unique non-pharmacological trials are being introduced and discussed.

Dr. Dodge's most recently completed NIA funded R01 examined whether stimulations through social interactions using modern communication technologies (pc, webcams and Internet) could improve cognitive functions.  Her current NIH-funded R01 projects are extensions of this previous study and examine the underlying mechanisms of improvement in cognitive functions using biomarkers.  She holds Fellow status at the Gerontological Society of America and serves as a statistical editor for several dementia related journals.

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  • Ph.D., Pennsylvania State University 1992


  • "Predicting mild cognitive impairment from spontaneous spoken utterances." Alzheimer's and Dementia: Translational Research and Clinical Interventions  In: , Vol. 3, No. 2, 01.06.2017, p. 219-228.
  • "Cohort effects in verbal memory function and practice effects : A population-based study." International Psychogeriatrics  In: , Vol. 29, No. 1, 01.01.2017, p. 137-148.
  • "Outcomes after diagnosis of mild cognitive impairment in a large autopsy series." Annals of Neurology In: , 2017.
  • "Willingness to Be a Brain Donor : A Survey of Research Volunteers From 4 Racial/Ethnic Groups." Alzheimer Disease and Associated Disorders In: , 24.10.2016.
  • "COMPASS : A computational model to predict changes in MMSE scores 24-months after initial assessment of Alzheimer's disease." Scientific Reports  In: , Vol. 6, 34567, 05.10.2016.
  • "Comparison of cerebral blood flow and structural penumbras in relation to white matter hyperintensities : A multi-modal magnetic resonance imaging study." Journal of Cerebral Blood Flow and Metabolism In: , Vol. 36, No. 9, 01.09.2016, p. 1528-1536.
  • "Longitudinal Relationship between Loneliness and Social Isolation in Older Adults : Results from the Cardiovascular Health Study." Journal of Aging and Health  In: , Vol. 28, No. 5, 01.08.2016, p. 775-795.
  • "Discriminative fusion of multiple brain networks for early mild cognitive impairment detection."   2016 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2016 - Proceedings. Vol. 2016-June IEEE Computer Society, 2016. p. 568-572 7493332.
  • "Less Daily Computer Use is Related to Smaller Hippocampal Volumes in Cognitively Intact Elderly." Journal of Alzheimer's Disease In: , Vol. 52, No. 2, 10.05.2016, p. 713-717.
  • "Associations between Serum Omega-3 Fatty Acid Levels and Cognitive Functions among Community-Dwelling Octogenarians in Okinawa, Japan : The KOCOA Study." Journal of Alzheimer's Disease In: , Vol. 51, No. 3, 30.03.2016, p. 857-866.
  • "Embedded Online Questionnaire Measures Are Sensitive to Identifying Mild Cognitive Impairment." Alzheimer Disease and Associated Disorders In: , Vol. 30, No. 2, 2016, p. 152-159.
  • "A Smart-Home System to Unobtrusively and Continuously Assess Loneliness in Older Adults." IEEE Journal of Translational Engineering in Health and Medicine  In: , Vol. 4, 7488979, 2016.
  • "Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology." Alzheimer's and Dementia  In: , 2016.
  • "Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease." Alzheimer's and Dementia In: , 2016.
  • "The prevalence of mild cognitive impairment in diverse geographical and ethnocultural regions : The COSMIC Collaboration." PLoS One  In: , Vol. 10, No. 11, e0142388, 05.11.2015.
  • "Results From the NACC Uniform Data Set Neuropsychological Battery Crosswalk Study." Alzheimer Disease and Associated Disorders  In: , 17.10.2015.
  • "Web-enabled conversational interactions as a method to improve cognitive functions : Results of a 6-week randomized controlled trial." Alzheimer's and Dementia: Translational Research and Clinical Interventions In: , Vol. 1, No. 1, 14.10.2015, p. 1-12.
  • "Use of high-frequency in-home monitoring data may reduce sample sizes needed in clinical trials." PLoS One In: , Vol. 10, No. 9, e0138095, 17.09.2015.
  • "Social markers of mild cognitive impairment : Proportion of word counts in free conversational speech." Current Alzheimer Research In: , Vol. 12, No. 6, 01.07.2015, p. 513-519.
  • "Characterizing the white matter hyperintensity penumbra with cerebral blood flow measures." NeuroImage: Clinical In: , Vol. 8, 08.06.2015, p. 224-229.
  • "Pervasive computing technologies to continuously assess Alzheimer's disease progression and intervention efficacy." Frontiers in Aging Neuroscience In: , Vol. 7, No. JUN, 102, 2015.
  • "Computer mouse movement patterns : A potential marker of mild cognitive impairment." Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring In: , Vol. 1, No. 4, 2015, p. 472-480.
  • "Corrigendum : Pervasive computing technologies to continuously assess Alzheimer's disease progression and intervention efficacy Front. [Aging Neurosci, (2015) 7, 102] DOI: 10.3389/fnagi.2015.00102." Frontiers in Aging Neuroscience In: , Vol. 7, No. DEC, 232, 2015.
  • "Characteristics associated with willingness to participate in a randomized controlled behavioral clinical trial using home-based personal computers and a webcam." Trials In: , Vol. 15, No. 1, 508, 23.12.2014.
  • "Biomarker progressions explain higher variability in stage-specific cognitive decline than baseline values in Alzheimer disease." Alzheimer's and Dementia In: , Vol. 10, No. 6, 01.11.2014, p. 690-703.
  • "Unobtrusive measurement of daily computer use to detect mild cognitive impairment." Alzheimer's and Dementia  In: , Vol. 10, No. 1, 01.2014, p. 10-17.
  • "A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease." Journal of Alzheimer's Disease  In: , Vol. 38, No. 1, 2014, p. 111-120.
  • "Cohort effects in age-associated cognitive trajectories." Journals of Gerontology - Series A Biological Sciences and Medical Sciences  In: , Vol. 69, No. 6, 2014, p. 687-694.
  • "Associations between observed in-home behaviors and self-reported low mood in community-dwelling older adults." Journal of the American Geriatrics Society In: , Vol. 62, No. 4, 2014, p. 685-689.
  • "Tools for advancing research into social networks and cognitive function in older adults." International Psychogeriatrics In: , Vol. 26, No. 4, 2014, p. 533-539.

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