Photo of Guang Fan, M.D., Ph.D.

Guang Fan M.D., Ph.D.

    • Professor of Pathology School of Medicine
    • Director, Flow Cytometry Laboratory
    • Program Director, Hematopathology Fellowship

Dr. Fan is an expert in diagnosis of leukemia, lymphoma, congenitial and acquired bone marrow failure disorders. 

Dr. Fan's research interest is in developing sensitive and advanced diagnotic tests for leukemia and lymphoma.

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Education

  • M.S., Beijing Medical University 1989
  • M.D., Beijing Medical University 1986
  • Ph.D., Wayne State University, Detroit Michigan 1992
  • Residency:

    • Anatomic and Clinical Pathology, University of Cincinnati, 1996-2000
  • Fellowship:

    • Hematopathology, Indiana University, 2000-2001
  • Certifications:

    • Anatomic and Clinical Pathology, American Board of Pathology, 2000
    • Hematology, American Board of Pathology, 2001

Publications

  • "Concurrent STAT3, DNMT3A, and TET2 mutations in T-LGL leukemia with molecularly distinct clonal hematopoiesis of indeterminate potential." American Journal of Hematology In: , Vol. 92, No. 1, 01.01.2017, p. E6-E8.
  • "Targeted next-generation sequencing in myelodysplastic syndrome and chronic myelomonocytic leukemia aids diagnosis in challenging cases and identifies frequent spliceosome mutations in transformed acute myeloid leukemia." American Journal of Clinical Pathology  In: , Vol. 145, No. 4, 01.04.2016, p. 497-506.
  • "MYD88 mutation analysis of a rare composite chronic lymphocyte leukemia and lymphoplasmacytic lymphoma by flow cytometry cell sorting." Annals of Hematology  In: , Vol. 94, No. 11, 22.11.2015, p. 1941-1944.
  • "The corepressor Rcor1 is essential for normal myeloerythroid lineage differentiation." Stem Cells In: , Vol. 33, No. 11, 01.11.2015, p. 3304-3314.
  • "Functional integration of acute myeloid leukemia into the vascular niche." Leukemia In: , Vol. 28, No. 10, 01.10.2014, p. 1978-1987.
  • "Aberrations of MYC are a common event in B-cell prolymphocytic leukemia." American Journal of Clinical Pathology  In: , Vol. 142, No. 3, 01.09.2014, p. 347-354.
  • "Corepressor Rcor1 is essential for murine erythropoiesis." Blood  In: , Vol. 123, No. 20, 15.05.2014, p. 3175-3184.
  • "Mutations in gamma adducin are associated with inherited cerebral palsy." Annals of Neurology  In: , Vol. 74, No. 6, 12.2013, p. 805-814.
  • "Early precursor T-lymphoblastic leukaemia/lymphoma arising from paediatric chronic myeloid leukaemia - unusual lymph node blast crisis." British Journal of Haematology  In: , Vol. 161, No. 1, 04.2013, p. 136-139.
  • "Kinase pathway dependence in primary human leukemias determined by rapid inhibitor screening." Cancer Research In: , Vol. 73, No. 1, 01.01.2013, p. 285-296.
  • "Diffuse large B-cell lymphoma in adults aged 75 years and older : A single institution analysis of cause-specific survival and prognostic factors." Therapeutic Advances in Hematology  In: , Vol. 4, No. 6, 2013, p. 349-353.
  • "Multiplex high-throughput gene mutation analysis in acute myeloid leukemia." Human Pathology  In: , Vol. 43, No. 12, 12.2012, p. 2167-2176.
  • "Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia." Leukemia In: , Vol. 26, No. 9, 09.2012, p. 2144-2146.
  • "RAS mutations in therapy-related acute myeloid leukemia after successful treatment of acute promyelocytic leukemia." Leukemia and Lymphoma  In: , Vol. 53, No. 5, 05.2012, p. 999-1002.
  • "Bone marrow involvement by peripheral t-cell lymphoma, not otherwise specified." Pathology Case Reviews  In: , Vol. 17, No. 3, 05.2012, p. 125-129.
  • "Systemic epstein-barr virus-positive t-cell lymphoproliferative disease of childhood." Pathology Case Reviews  In: , Vol. 17, No. 3, 05.2012, p. 120-124.
  • "Association of JAK2 mutation status and cytogenetic abnormalities in myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms." American Journal of Clinical Pathology  In: , Vol. 135, No. 5, 05.2011, p. 709-719.
  • "Immunophenotypic correlation between skin biopsy and peripheral blood findings in mycosis fungoides." American Journal of Clinical Pathology  In: , Vol. 134, No. 5, 11.2010, p. 739-748.
  • "Immunophenotypic variations of Burkitt lymphoma." American Journal of Clinical Pathology  In: , Vol. 134, No. 1, 07.2010, p. 127-138.
  • "Nuclear expression of sox11 is highly associated with mantle cell lymphoma but is independent of t(11;14)(q13;q32) in non-mantle cell B-cell neoplasms." Modern Pathology In: , Vol. 23, No. 1, 01.2010, p. 105-112.
  • "Rejection Versus Posttransplantation Lymphoproliferative Disorder in a Renal Transplant Recipient." American Journal of Kidney Diseases In: , Vol. 52, No. 6, 12.2008, p. 1174-1179.
  • "Response to donner : Letter to the editor." Pediatric and Developmental Pathology  In: , Vol. 11, No. 4, 07.2008, p. 326.
  • "The saga of JAK2 mutations and translocations in hematologic disorders : pathogenesis, diagnostic and therapeutic prospects, and revised World Health Organization diagnostic criteria for myeloproliferative neoplasms." Human Pathology  In: , Vol. 39, No. 6, 06.2008, p. 795-810.
  • "A unique case of adolescent CD56-negative extranodal NK/T-cell lymphoma, nasal type." Pediatric and Developmental Pathology  In: , Vol. 11, No. 1, 01.2008, p. 50-54.
  • "TandTRAQ : An open-source tool for integrated protein identification and quantitation." Bioinformatics  In: , Vol. 23, No. 24, 12.2007, p. 3394-3396.
  • "Drug resistance in B-cell chronic lymphocytic leukemia : Predictable by in vitro evaluation with a multiparameter flow cytometric cytotoxicity assay." Cytometry Part B - Clinical Cytometry In: , Vol. 72, No. 3, 15.05.2007, p. 189-195.
  • "B-cell lymphomas."   Molecular Pathology in Clinical Practice. Springer New York, 2007. p. 349-364.
  • "Aberrant stabilization of c-Myc protein in some lymphoblastic leukemias." Leukemia In: , Vol. 20, No. 9, 09.2006, p. 1572-1581.
  • "Proteomic profiling of mature CD10+ B-cell lymphomas." American Journal of Clinical Pathology  In: , Vol. 124, No. 6, 12.2005, p. 920-929.
  • "Diagnostic usefulness of aberrant CD22 expression in differentiating neoplastic cells of B-cell chronic lymphoproliferative disorders from admixed benign B cells in four-color multiparameter flow cytometry." American Journal of Clinical Pathology  In: , Vol. 123, No. 6, 06.2005, p. 826-832.

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