Photo of David Kabat, Ph.D.

David Kabat Ph.D.

  • 5034948442

Publications

  • "Movements of HIV-1 genomic RNA-APOBEC3F complexes and PKR reveal cytoplasmic and nuclear PKR defenses and HIV-1 evasion strategies." Virus Research  In: , Vol. 213, 02.02.2016, p. 124-139.
  • "Short Communication : HIV-1 Variants That Use Mouse CCR5 Reveal Critical Interactions of gp120's V3 Crown with CCR5 Extracellular Loop 1." AIDS Research and Human Retroviruses  In: , Vol. 31, No. 10, 01.10.2015, p. 992-998.
  • "Reversible and efficient activation of HIV-1 cell entry by a tyrosine-sulfated peptide dissects endocytic entry and inhibitor mechanisms." Journal of Virology  In: , Vol. 88, No. 8, 2014, p. 4304-4318.
  • "RRE-dependent HIV-1 Env RNA effects on Gag protein expression, assembly and release." Virology  In: , Vol. 462-463, No. 1, 2014, p. 126-134.
  • "Kinetic mechanism for HIV-1 neutralization by antibody 2G12 entails reversible glycan binding that slows cell entry." Proceedings of the National Academy of Sciences of the United States of America  In: , Vol. 109, No. 20, 15.05.2012, p. 7829-7834.
  • "Rapid dissociation of HIV-1 from cultured cells severely limits infectivity assays, causes the inactivation ascribed to entry inhibitors, and masks the inherently high level of infectivity of virions." Journal of Virology  In: , Vol. 84, No. 6, 03.2010, p. 3106-3110.
  • "Evidence that ecotropic murine leukemia virus contamination in TZM-bl cells does not affect the outcome of neutralizing antibody assays with human immunodeficiency virus type 1." Journal of Virology In: , Vol. 83, No. 16, 08.2009, p. 8289-8292.
  • "Human immunodeficiency virus type 1 Vif functionally interacts with diverse APOBEC3 cytidine deaminases and moves with them between cytoplasmic sites of mRNA metabolism." Journal of Virology  In: , Vol. 82, No. 2, 01.2008, p. 987-998.
  • "An Allosteric Rheostat in HIV-1 gp120 Reduces CCR5 Stoichiometry Required for Membrane Fusion and Overcomes Diverse Entry Limitations." Journal of Molecular Biology  In: , Vol. 374, No. 1, 16.11.2007, p. 64-79.
  • "The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment." Retrovirology  In: , Vol. 4, 55, 08.08.2007.
  • "The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules." Journal of Biological Chemistry  In: , Vol. 281, No. 39, 29.09.2006, p. 29105-29119.
  • "CCR5 N-terminal region plays a critical role in HIV-1 inhibition by Toxoplasma gondii-derived cyclophilin-18." Journal of Biological Chemistry  In: , Vol. 280, No. 33, 19.08.2005, p. 29570-29577.
  • "Regulated production and anti-HIV type 1 activities of cytidine deaminases APOBEC3B, 3F, and 3G." AIDS Research and Human Retroviruses  In: , Vol. 21, No. 7, 07.2005, p. 611-619.
  • "Kinetic factors control efficiencies of cell entry, efficacies of entry inhibitors, and mechanisms of adaptation of human immunodeficiency virus." Journal of Virology  In: , Vol. 79, No. 7, 04.2005, p. 4347-4356.
  • "Variants of human immunodeficiency virus type 1 that efficiently use CCR5 lacking the tyrosine-sulfated amino terminus have adaptive mutations in gp120, including loss of a functional N-glycan." Journal of Virology  In: , Vol. 79, No. 7, 04.2005, p. 4357-4368.
  • "Role of low CD4 levels in the influence of human immunodeficiency virus type 1 envelope V1 and V2 regions on entry and spread in macrophages." Journal of Virology  In: , Vol. 79, No. 8, 04.2005, p. 4828-4837.
  • "Transcriptional regulation of APOBEC3G, a cytidine deaminase that hypermutates human immunodeficiency virus." Journal of Biological Chemistry  In: , Vol. 279, No. 40, 01.10.2004, p. 41744-41749.
  • "Porcine endogenous retroviruses infect cells lacking cognate receptors by an alternative pathway : Implications for retrovirus evolution and xenotransplantation." Journal of Virology  In: , Vol. 78, No. 16, 08.2004, p. 8868-8877.
  • "The viral infectivity factor (Vif) of HIV-1 unveiled." Trends in Molecular Medicine  In: , Vol. 10, No. 6, 01.06.2004, p. 291-297.
  • "HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation." Nature Medicine  In: , Vol. 9, No. 11, 11.2003, p. 1398-1403.
  • "N-linked glycosylation and sequence changes in a critical negative control region of the ASCT1 and ASCT2 neutral amino acid transporters determine their retroviral receptor functions." Journal of Virology  In: , Vol. 77, No. 5, 03.2003, p. 2936-2945.
  • "Cell surface receptors for gammaretroviruses." Current Topics in Microbiology and Immunology In: , Vol. 281, 2003, p. 29-106.
  • "Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1." Journal of Virology  In: , Vol. 76, No. 21, 11.2002, p. 11133-11138.
  • "Segregation of CD4 and CXCR4 into distinct lipid microdomains in T lymphocytes suggests a mechanism for membrane destabilization by human immunodeficiency virus." Journal of Virology  In: , Vol. 76, No. 4, 2002, p. 1802-1815.
  • "The envelope glycoprotein of human endogenous retrovirus type W uses a divergent family of amino acid transporters/cell surface receptors." Journal of Virology  In: , Vol. 76, No. 13, 2002, p. 6442-6452.
  • "Truncated Forms of the Dual Function Human ASCT2 Neutral Amino Acid Transporter/Retroviral Receptor Are Translationally Initiated at Multiple Alternative CUG and GUG Codons." Journal of Biological Chemistry  In: , Vol. 276, No. 29, 20.07.2001, p. 27221-27230.
  • "Adaptive mutations in the V3 loop of gp120 enhance fusogenicity of human immunodeficiency virus type 1 and enable use of a CCR5 coreceptor that lacks the amino-terminal sulfated region." Journal of Virology In: , Vol. 75, No. 24, 2001, p. 12266-12278.
  • "Frequent substitution polymorphisms in African green monkey CCR5 cluster at critical sites for infections by simian immunodeficiency virus SIVagm, implying ancient virus-host coevolution." Journal of Virology In: , Vol. 75, No. 18, 2001, p. 8449-8460.
  • "Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1." Journal of Virology  In: , Vol. 74, No. 15, 08.2000, p. 7005-7015.
  • "Critical role of enhanced CD4 affinity in laboratory adaptation of human immunodeficiency virus type 1." AIDS Research and Human Retroviruses  In: , Vol. 16, No. 9, 10.06.2000, p. 871-882.

Additional information

Edit profile