Photo of Charles Roselli, Ph.D.

Charles Roselli Ph.D.

    • Professor of Physiology and Pharmacology School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Ph.D., Hahnemann University, 1981

Memberships and associations

  • SOM-Physiology &Pharmacology DepartmentNeuroscience Graduate Program Physiology &PharmacologyProgram in Molecular &Cellular Biosciences


  • "Early prenatal androgen exposure reduces testes size and sperm concentration in sheep without altering neuroendocrine differentiation and masculine sexual behavior." Domestic Animal Endocrinology In: , Vol. 62, 01.01.2018, p. 1-9.
  • "Tyrosine hydroxylase in the ventral tegmental area of rams with high or low libido—A role for dopamine." Animal Reproduction Science In: , Vol. 187, 01.12.2017, p. 152-158.
  • "Fos expression in the olfactory pathway of high- and low-sexually performing rams exposed to urine from estrous or ovariectomized ewes." Applied Animal Behaviour Science  In: , Vol. 186, 01.01.2017, p. 22-28.
  • "Excess testosterone exposure alters hypothalamic-pituitary-Testicular axis dynamics and gene expression in sheep fetuses." Endocrinology In: , Vol. 157, No. 11, 01.11.2016, p. 4234-4245.
  • "Developmental and Functional Effects of Steroid Hormones on the Neuroendocrine Axis and Spinal Cord." Journal of Neuroendocrinology In: , Vol. 28, No. 7, 01.07.2016.
  • "Effects of Long-Term Flutamide Treatment During Development on Sexual Behaviour and Hormone Responsiveness in Rams." Journal of Neuroendocrinology In: , Vol. 28, No. 5, 01.05.2016.
  • "Effect of testosterone on neuronal morphology and neuritic growth of fetal lamb hypothalamus-preoptic area and cerebral cortex in primary culture." PLoS One  In: , Vol. 10, No. 6, 08.06.2015.
  • "Prenatal influence of an androgen agonist and antagonist on the differentiation of the ovine sexually dimorphic nucleus in male and female lamb fetuses." Endocrinology In: , Vol. 155, No. 12, 01.12.2014, p. 5000-5010.
  • "Cell death in the central division of the medial preoptic nucleus of male and female lamb fetuses." Brain Research In: , Vol. 1554, 20.03.2014, p. 21-28.
  • "Sex differences in expression of oestrogen receptor α but not androgen receptor mRNAs in the foetal lamb brain." Journal of Neuroendocrinology In: , Vol. 26, No. 5, 2014, p. 321-328.
  • "Rapid effects of 17β-estradiol on male copulatory behaviors are not elicited by the novel membrane active estrogenic compound STX." Behavioral Neuroscience In: , Vol. 127, No. 4, 08.2013, p. 598-605.
  • "Neonatal testosterone exposure protects adult male rats from stroke." Neuroendocrinology In: , Vol. 97, No. 3, 04.2013, p. 271-282.
  • "The Distribution and Regulation of Aromatase in the Mammalian Brain : from Mice to Monkeys."  Brain Aromatase, Estrogens, and Behavior. Oxford University Press, 2013.
  • "Ontogeny of Cytochrome P450 Aromatase mRNA Expression in the Developing Sheep Brain." Journal of Neuroendocrinology In: , Vol. 24, No. 3, 03.2012, p. 443-452.
  • "Localization of brain 5α-reductase messenger RNA in mice selectively bred for high chronic alcohol withdrawal severity." Alcohol In: , Vol. 45, No. 8, 12.2011, p. 763-772.
  • "Separate critical periods exist for testosterone-induced differentiation of the brain and genitals in sheep." Endocrinology  In: , Vol. 152, No. 6, 06.2011, p. 2409-2415.
  • "Sexual differentiation of sexual behavior and its orientation." Frontiers in Neuroendocrinology  In: , Vol. 32, No. 2, 04.2011, p. 109.
  • "The development of male-oriented behavior in rams." Frontiers in Neuroendocrinology In: , Vol. 32, No. 2, 04.2011, p. 164-169.
  • "Wired on steroids : Sexual differentiation of the brain and its role in the expression of sexual partner preferences." Frontiers in Endocrinology In: , Vol. 2, No. OCT, Article 42, 2011.
  • "The ovine sexually dimorphic nucleus, aromatase, and sexual partner preferences in sheep." Journal of Steroid Biochemistry and Molecular Biology In: , Vol. 118, No. 4-5, 28.02.2010, p. 252-256.
  • "Cognition is not modified by large but temporary changes in sex hormones in men." Journal of Clinical Endocrinology and Metabolism In: , Vol. 95, No. 1, 01.2010, p. 280-288.
  • "Prenatal exposure to vinclozolin disrupts selective aspects of the gonadotrophin-releasing hormone neuronal system of the rabbit." Journal of Neuroendocrinology In: , Vol. 22, No. 6, 2010, p. 518-526.
  • "Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5α-Reductase Enzyme Activity and Expression." Alcoholism: Clinical and Experimental Research In: , Vol. 33, No. 12, 12.2009, p. 2077-2087.
  • "Porcine hypothalamic aromatase cytochrome P450 : Isoform characterization, sex-dependent activity, regional expression, and regulation by enzyme inhibition in neonatal boars." Biology of Reproduction In: , Vol. 81, No. 2, 08.2009, p. 388-395.
  • "The neurobiology of sexual partner preferences in rams." Hormones and Behavior  In: , Vol. 55, No. 5, 05.2009, p. 611-620.
  • "Brain aromatization : Classic roles and new perspectives." Seminars in Reproductive Medicine In: , Vol. 27, No. 3, 05.2009, p. 207-217.
  • "The amphibian (rana esculenta) brain progesterone receptor : Relationship to plasma steroids and vitellogenic cycle during the gonadal recovery phase."   Annals of the New York Academy of Sciences. Vol. 1163 2009. p. 407-409 (Annals of the New York Academy of Sciences; Vol. 1163).
  • "The volume of the ovine sexually dimorphic nucleus of the preoptic area is independent of adult testosterone concentrations." Brain Research In: , Vol. 1249, 16.01.2009, p. 113-117.
  • "Age-dependent effects of testosterone in experimental stroke." Journal of Cerebral Blood Flow and Metabolism In: , Vol. 29, No. 3, 2009, p. 486-494.
  • "Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity." International Journal of Oncology In: , Vol. 34, No. 5, 2009, p. 1319-1327.

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