Photo of Cary O. Harding, M.D.

Cary O. Harding M.D.

  • (503) 494-8307
    • Professor of Molecular and Medical Genetics School of Medicine
    • Molecular and Medical Genetics Graduate Program School of Medicine

Dr. Harding received his medical degree in 1987 from the University of Washington School of Medicine in Seattle. He completed his pediatrics residency and fellowship in molecular and medical genetics and pediatrics at the University of Wisconson in Madison. Dr. Harding is fluent in German.

  • Residency:

    • University of Wisconsin Hospital, Madison
  • Fellowship:

    • Fellowship in molecular and medical genetics and pediatrics, University of Wisconsin
  • Certifications:

    • National Board of Medical Examiners, 1988

Publications

  • "Triheptanoin versus trioctanoin for long-chain fatty acid oxidation disorders : a double blinded, randomized controlled trial." Journal of Inherited Metabolic Disease  In: , 04.09.2017, p. 1-13.
  • "Low-Dose Gene Therapy for Murine PKU Using Episomal Naked DNA Vectors Expressing PAH from Its Endogenous Liver Promoter." Molecular Therapy - Nucleic Acids  In: , Vol. 7, 01.06.2017, p. 339-349.
  • "Fatty acid β-oxidation defects."  Metabolic Diseases: Foundations of Clinical Management, Genetics, and Pathology. IOS Press, 2017. p. 155-189.
  • "Safety and efficacy of glycerol phenylbutyrate for management of urea cycle disorders in patients aged 2months to 2years." Molecular Genetics and Metabolism  In: , 2017.
  • "Characterization of Chorioretinopathy Associated with Mitochondrial Trifunctional Protein Disorders : Long-Term Follow-up of 21 Cases." Ophthalmology In: , Vol. 123, No. 10, 01.10.2016, p. 2183-2195.
  • "Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1." Science Translational Medicine In: , Vol. 8, No. 349, 349ra99, 27.07.2016.
  • "Spectrum of ocular manifestations in cobalamin C and cobalamin A types of methylmalonic acidemia." Ophthalmic Genetics In: , 16.03.2016, p. 1-11.
  • "Patients' ratings of genetic conditions validate a taxonomy to simplify decisions about preconception carrier screening via genome sequencing." American Journal of Medical Genetics, Part A  In: , Vol. 170, No. 3, 01.03.2016, p. 574-582.
  • "Generating a taxonomy for genetic conditions relevant to reproductive planning." American Journal of Medical Genetics, Part A In: , Vol. 170, No. 3, 01.03.2016, p. 565-573.
  • "Normal vitamin D levels and bone mineral density among children with inborn errors of metabolism consuming medical food-based diets." Nutrition Research In: , Vol. 36, No. 1, 01.01.2016, p. 101-108.
  • "High dose sapropterin dihydrochloride therapy improves monoamine neurotransmitter turnover in murine phenylketonuria (PKU)." Molecular Genetics and Metabolism In: , Vol. 117, No. 1, 01.01.2016, p. 5-11.
  • "Glutamine and hyperammonemic crises in patients with urea cycle disorders." Molecular Genetics and Metabolism In: , Vol. 117, No. 1, 01.01.2016, p. 27-32.
  • "Urinary phenylacetylglutamine (U-PAGN) concentration as biomarker for adherence in patients with urea cycle disorders (UCD) treated with glycerol phenylbutyrate." Molecular Genetics and Metabolism Reports In: , Vol. 5, 01.12.2015, p. 12-14.
  • "Self-reported treatment-associated symptoms among patients with urea cycle disorders participating in glycerol phenylbutyrate clinical trials." Molecular Genetics and Metabolism  In: , Vol. 116, No. 1-2, 01.09.2015, p. 29-34.
  • "Age-Related Accumulation of Somatic Mitochondrial DNA Mutations in Adult-Derived Human iPSCs." Cell Stem Cell  In: , 01.09.2015.
  • "Blood ammonia and glutamine as predictors of hyperammonemic crises in patients with urea cycle disorder." Genetics in Medicine  In: , Vol. 17, No. 7, 02.07.2015, p. 561-568.
  • "Erratum : Blood ammonia and glutamine as predictors of hyperammonemic crises in patients with urea cycle disorder (Genetics in Medicine (2014))." Genetics in Medicine In: , Vol. 17, No. 5, 08.05.2015, p. 427.
  • "Sodium phenylbutyrate decreases plasma branched-chain amino acids in patients with urea cycle disorders." Molecular Genetics and Metabolism  In: , Vol. 113, No. 1, 01.09.2014, p. 131-135.
  • "A longitudinal study of urea cycle disorders." Molecular Genetics and Metabolism  In: , Vol. 113, No. 1, 01.09.2014, p. 127-130.
  • "Pharmacologic inhibition of L-tyrosine degradation ameliorates cerebral dopamine deficiency in murine phenylketonuria (PKU)." Journal of Inherited Metabolic Disease  In: , Vol. 37, No. 5, 01.09.2014, p. 735-743.
  • "Infants suspected to have very-long chain acyl-CoA dehydrogenase deficiency from newborn screening." Molecular Genetics and Metabolism  In: , Vol. 111, No. 4, 2014, p. 484-492.
  • "Phenylketonuria scientific review conference : State of the science and future research needs." Molecular Genetics and Metabolism In: , Vol. 112, No. 2, 2014, p. 87-122.
  • "Use of propofol for short duration procedures in children with long chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) or trifunctional protein (TFP) deficiencies." Molecular Genetics and Metabolism In: , Vol. 112, No. 2, 2014, p. 139-142.
  • "Fumarylacetoacetate hydrolase deficient pigs are a novel large animal model of metabolic liver disease." Stem Cell Research In: , Vol. 13, No. 1, 2014, p. 144-153.
  • "A sensitive assay system to test antisense oligonucleotides for splice suppression therapy in the mouse liver." Molecular Therapy - Nucleic Acids In: , Vol. 3, 2014, p. e193.
  • "Single-dose, subcutaneous recombinant phenylalanine ammonia lyase conjugated with polyethylene glycol in adult patients with phenylketonuria : An open-label, multicentre, phase 1 dose-escalation trial." The Lancet  In: , Vol. 384, No. 9937, 2014, p. 37-44.
  • "Treatment of phenylketonuria using minicircle-based naked-DNA gene transfer to murine liver." Hepatology  In: , Vol. 60, No. 3, 2014, p. 1035-1043.
  • "Seeking a cure for the royal pain." Human Gene Therapy In: , Vol. 24, No. 12, 01.12.2013, p. 968-969.
  • "Altered body composition and energy expenditure but normal glucose tolerance among humans with a long-chain fatty acid oxidation disorder." American Journal of Physiology - Endocrinology and Metabolism In: , Vol. 305, No. 10, 15.11.2013.
  • "Expanding research to provide an evidence base for nutritional interventions for the management of inborn errors of metabolism." Molecular Genetics and Metabolism In: , Vol. 109, No. 4, 08.2013, p. 319-328.

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