KIT Gene Mutations In Malignant Melanoma
Test Description
Screening for KIT kinase gene mutations in cases of malignant melanoma is performed using assays developed by Michael Heinrich, MD, and Christopher Corless, MD, PhD. Detection methods include high-resolution melting curve analysis and DNA sequencing. The KIT gene exons that are screened in melanoma cases are exons 11, 13 and 17.
How To Order This Test
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To order GIST mutation screening, send the following items to Dr. Corless at the address below.
- Completed Test Requisition Form.
- A paraffin block or 15 unstained slides (uncharged slides preferred) representative of the tumor.
- A copy of the original pathology report.
- Patient’s billing information.
Send to: Dr. Christopher Corless
OHSU Dept. of Pathology (L471)
3181 SW Sam Jackson Park Rd
Portland, OR 97239
Ph: 503-494-6776
For additional information, contact Knight Diagnostic Laboratory Services Center at 503-494-5400.
| CPT code | |
| Lysis of Cells, Paraffin | 83907 |
| DNA extraction | 83890 |
| Enzymatic digestion | 83892 |
| PCR (per exon) | 83898 |
| HPLC (1st two exons) | 83903 |
| HPLC (additional exons) | 83903 |
| DNA sequencing | 83904 |
| Allele-specific PCR | 83905 |
| *Professional Fee | 88321 |
*Note: A professional pathology consultation fee is charged for all GIST cases.
Links: Back to Knight Diagnostic PTRL, Research Tests Available, CPT Codes and Charges, Background Information