GI Stromal Tumor (GIST)
Test Description
Screening for KIT and PDGFRA kinase gene mutations in GI stromal sarcomas (GISTs) is performed using a combination of assays developed by Michael Heinrich, MD, and Christopher Corless, MD, PhD. Detection methods include denaturing HPLC (Transgenomic WAVE™ system), melting curve analyses using FRET-probes, real-time PCR with mutation-specific dual-labeled probes, and DNA sequencing. With over 1,600 GISTs analyzed in our laboratories, we have the experience to provide excellent service in GIST genotyping.
How To Order This Test
To order GIST mutation screening, send the following items to Dr. Corless at the address below.
- Completed Test Requisition Form.
- A paraffin block or 10 unstained slides representative of the tumor.
- A copy of the original pathology report.
- Patient’s billing information.
Send to: Dr. Christopher Corless
OHSU Dept. of Pathology (L471)
3181 SW Sam Jackson Park Rd
Portland, OR 97239
Ph: 503-494-6776
For additional information, contact Rebecca Lewis (lewisr@ohsu.edu).
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