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GI Stromal Tumor (GIST)

Test Description

Screening for KIT and PDGFRA kinase gene mutations in GI stromal sarcomas (GISTs) is performed using a combination of assays developed by Michael Heinrich, MD, and Christopher Corless, MD, PhD. Detection methods include high-resolution melting curve analysis, real-time PCR with mutation-specific dual-labeled probes, and DNA sequencing. With over 1,600 GISTs analyzed in our laboratories, we have the experience to provide excellent service in GIST genotyping.

How To Order This Test

To order GIST mutation screening, send the following items to Dr. Corless at the address below.

  1. Completed Test Requisition Form.
  2. A paraffin block or 15 unstained slides (uncharged slides preferred) representative of the tumor.
  3. A copy of the original pathology report.
  4. Patient’s billing information.

Send to: Dr. Christopher Corless
    OHSU Dept. of Pathology (L471)
    3181 SW Sam Jackson Park Rd
    Portland, OR 97239
    Ph: 503-494-6776

For additional information, contact Knight Diagnostic Laboratory Services Center at 503-494-5400.

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