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The OHSU Renal Biopsy Service



What is an adequate renal biopsy specimen?

Native Kidney Biopsy
At least two cores of renal cortex (1 to 2 cm each) are recommended to assure an adequate sample. When a thin biopsy needle (18 gauge) is used, an additional core is recommended. If an adequate specimen cannot be obtained, a decision will have to be made before the tissue is placed into fixative, as to which one or two of the recommended studies should be requested (see "Dividing the limited specimen" and/or contact one of us to discuss this.

Transplant Kidney Biopsy
An adequate transplant kidney biopsy to evaluate for rejection consists of at least two needle core segments, each containing renal cortex (see "Dividing the allograft kidney biopsy").