Neuropathology Gross Description

Neuropath Gross Description: Normal adult brain
(Any gross lesions should be described in the appropriate location. Variations in the method of cutting should be appropriately noted.)

Neuropathology Gross Description: The fixed brain and dura are available for examination. The dura is grossly normal, with no evidence of hemorrhage. The fixed brain weight is 1110 grams. The cerebral hemispheres are symmetrical and have a normal gyral pattern. The leptomeninges are thin and translucent and have no exudates or hemorrhage. The vessels of the circle of Willis have a normal distribution and no atherosclerosis or aneurysms. The cranial nerves are identified in their normal anatomical locations and are unremarkable. There is no evidence of cerebellar tonsillar or uncal herniation.

The brainstem and cerebellum are separated from the cerebral hemispheres at the level of the midbrain. Serial coronal sections of the cerebral hemispheres show lateral and third ventricles of normal size. The gray-white junctions are distinct and the cortex, white matter and deep gray nuclei have no gross abnormalities. Serial transverse sections through the brainstem reveal normal pigmentation of the substantia nigra. The aqueduct and fourth ventricle are normal. The pons and medulla are grossly unremarkable. Serial sagittal sections of the cerebellum show no focal lesions.

Neuropathology Cassette Index:
B1, pituitary
B2, frontal cortex (indicate right/left for all subsequent sections)
B3, occipital cortex
B4, hippocampus
B5, basal ganglia
B6, thalamus
B7, cerebellum (cortex and dentate)
B8, midbrain
B9, pons
B10, medulla

Submit additional sections as indicated, including representative sections of lesions. Insert in the appropriate location: e.g. cortical lesions with other sections of cortex, brainstem lesions with other brainstem sections.