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Randall Woltjer, MD, PhD
Neuropathologist; Director, Neuropathology Core of the Layton Aging & Alzheimer’s Disease Center
Rank: Associate Professor
Clinical Services: Neuropathology
Clinical Interests: Neuropathology, Autopsy Pathology of Neurodegenerative Diseases
Research Interests: Biochemical Pathology of Neurodegenerative Diseases such as Alzheimer's disease; Biochemical Characteristics of Normal Aging
 
Education:
1994    MD     Vanderbilt University School of Medicine
1992    PhD    Biochemistry    Vanderbilt University
1986    MA     English            Michigan State University
1985    BS      Physics            Calvin College
Boards:
2005    Neuropathology
2000    Anatomic and Clinical Pathology
1995    National Board of Medical Examiners
Previous Position:
2002-2006    Acting Assistant Professor, Department of Pathology, University of Washington, Seattle, Washington
Selected References:
  1. Hoshino, A., Yee, C.J., Campbell, M., Woltjer, R.L., Townsend, R.L., van der Meer, R., Shur, Y., Holt, J.T., Moses, H.L., and Jensen, R.A. Effects of BRCA1 transgene expression on murine mammary gland development and mutagen-induced mammary neoplasia. International Journal of Biological Sciences, in press.
     
  2. Woltjer, R.L., McMahan, W., Milatovic, D., Kjerulf, J.D., Shie, F.-S., Rung, L.G., Montine, K.S., and Montine, T.J. Effects of chemical chaperones on oxidative stress and detergent-insoluble species formation following conditional expression of amyloid precursor protein carboxy-terminal fragment. Neurobiology of Disease, 25:427-37, 2007.
     
  3. Montine, T.J., Woltjer, R.L., Pan, C., Montine, K.S., and Zhang, J. Liquid chromatography with tandem mass spectrometry-based proteomic discovery in aging and Alzheimer's disease. NeuroRx., 3:336-43, 2006.
     
  4. Boutte, A.M., Woltjer, R.L., Wang, Q., Zimmerman, L.J., Stamer, S.L, Montine, K.S., Manno, M.V., Cimino, P.J., Liebler, D.C., and Montine, T.J. Map of selectively increased oxidative modifications on detergent-insoluble forms of Aβ and β-III tubulin in Alzheimer’s disease. FASEB J., 20:1473-83, 2006.
     
  5. Woltjer, R.L., Cimino, P.J., Boutte, A.M., Schantz, A.M., Montine, K.S., Larson, E.B., Bird, T., Quinn, J.F., Zhang, J., and Montine T.J. Proteomic determination of widespread detergent-insolubility including Abeta but not tau early in the pathogenesis of Alzheimer’s disease. FASEB J. 19:1923-5, 2005.
     
  6. Woltjer, R.L., Nghiem, W., Maezawa, I., Milatovic, D., Vaisar, T., Montine, K.S., and Montine, T.J. Role of glutathione in intracellular amyloid-β precursor protein/carboxy-terminal fragment aggregation and associated cytotoxicity. J Neurochem. 93:1047-56. 2005.
     

Last Updated: 08/09/2010