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Megan Troxell, MD, PhD
Medical Director, Immunohistochemistry Lab
Rank: Associate Professor
Clinical Services: Surgical Pathology, Cytopathology, Renal Pathology, Immunohistochemistry
Clinical Interests: Renal Pathology, Immunohistochemistry, GU pathology, Breast Pathology, Transplantation Pathology, Surgical Pathology
Research Interests: Renal Pathology, Immunohistochemistry, GU Pathology, Breast Pathology, Transplantation Pathology
2003-2004               Renal Pathology & Immunohistology Fellow, Stanford University, Co-Chief Resident,                                 Pathology, Stanford University Medical Center
2002-2003               Surgical Pathology Fellow, Stanford University Medical Center
2000-2002               Resident in Pathology, Stanford University Medical Center
1991-2000               M.D./Ph.D.Stanford University
2004  Anatomic Pathology
Previous Position:
July 2004-2005        Clinician Educator, Surgical Pathology, Stanford University
Selected References:
  • Troxell ML, DC Houghton, M Hawkey, TD Batiuk, WM Bennett. "Enteric oxalate nephropathy in the renal allograft: an underrecognized complication of bariatric surgery." (2013) Am J Transplant. 13(2):501-9.doi: 10.1111/ajt.12029. doi: 10.1111/ajt.12029. [Epub ahead of print]
  • Flatley E, D Ang , AWarrick, C Beadling, CL Corless, ML Troxell. "PIK3CA-AKT Pathway Mutations in Micropapillary Breast Carcinoma" Human Pathology. doi:pii: S0046-8177(12)00401-7. 10.1016/j.humpath.2012.10.018. [Epub ahead of print] PMID: 23352210
  • Kehr EL, Jorns JM, Ang D, Warrick A, Neff T, Degnin M, Lewis R, Beadling C, Corless CL, Troxell ML. Mucinous Breast Carcinomas Lack PIK3CA and AKT1 Mutations. Hum Pathol. (2012) Dec;43(12):2207-12 PMID: 22705004
  • Troxell, ML, AL Brunner, T Neff, AWarrick, C Beadling, K Montgomery, S Zhu, CL Corless, RB West. "Phosphatidylinositol-3-kinase pathway mutations are common in breast columnar cell lesions" (2012) Mod Pathol. 25(7):930-7 PMID:22460814 epub Mar 30 2012.
  • Troxell, ML. "PIK3CA/AKT1 Mutations in Breast Carcinoma: a Comprehensive Review of Experimental and Clinical Studies" Journal of Clinical and Experimental Pathology. In press. S1:002. doi:10.4172/2161-0681.S1-002
  • Davis, JD., L. Matsumura, DA. Weeks, ML. Troxell. "PAX2 expression in Wilms tumors and other childhood neoplasms" (2011) Am J Surg Pathol. 35(8):1186-94. PMID: 21730820.
  • Houghton DC., ML. Troxell. "An Abundance of IgG4+ Plasma Cells is not Specific for IgG4-Related Tubulointerstitial Nephritis" Mod Pathol. PMID: 2170153.
  • Troxell, M.L., D. Norman, A. Mittalhenkle. "Glomerular Fibrin Thrombi in ABO and Crossmatch Compatible Renal Allograft Biopsies" (2011) Pathology Research & Practice. 207(1):15-23. PMID: 21067871.
  • Go, S., M. Conlin, J. E. Hooper, M. L. Troxell. "Polyoma Virus Nephropathy-Related Mass Lesion in an Apparently Immunocompetent Patient", Int Urol Nephrol. PMID: 21559788
  • Prikis, M., D. Norman, S. Rayhill, A. Olyaei, M. L. Troxell, A. Mittalhenkle. "Preserved endocrine function in a pancreas transplant with pancreatic panniculitis and antibody-mediated rejection" (2010) Am J Transplant. 10:2717-22
  • Jensen, A., A. Naik, R. Pommier, J. Vetto, M. Troxell "Factors Influencing Accuracy of Axillary Sentinel Lymph Node Frozen Section." (2010) Am. J Surg. 199:629-35.
  • Troxell, M.L., J. Levine, C. Beadling, A. Warrick, J. Dunlap, A. Presnell, J. Patterson, A. Shukla, N. R. Olson, M. C. Heinrich, C. L. Corless "High Prevalence of PIK3CA-AKT Pathway Mutations in Papillary Neoplasms of the Breast" (2010) Modern Pathology. 23(1): 27-37.
  • Troxell, M.L., D.B. Koslin, D. Norman, S. Rayhill, A. Mittalhenkle "Pancreas Allograft Rejection: Analysis of Concurrent Renal Allograft Biopsies and Post-therapy Follow-up Biopsies" (2010) Transplantation. 90(1):75-84.
  • Dunlap, J.B., C. Le, A. Shukla J. Patterson, A. Presnell, M. C. Heinrich, C. L. Corless, M. L. Troxell. "Phosphatidylinositol-3-Kinase and AKT1 Mutations Occur Early in Breast Carcinoma" (2010) Breast Cancer Research & Treatment. 120(2):409-18. DOI 10.1007/s10549-009-0406-1
  • Schreiner, A., S. Daneshmand, A. Bayne, G. Countryman, C. L. Corless, M.L. Troxell. "Distinctive Morphology of Renal Cell Carcinomas in a Tuberous Sclerosis Patient" 2009. Int. J. Surg. Pathol. doi:10.1177/1066896909333510
  • M.L. Troxell. , Dunlap JB, Mittalhenkle A, Ishag M, Fan G, Huang JZ, Gatter K, Byrd DM, Webster D, Houghton DC. Rejection Versus Posttransplantation Lymphoproliferative Disorder in a Renal Transplant Recipient. Am J Kidney Dis. 2008 Aug 14. 52(6):1174-9. PMID: 18706749
  • Troxell, M.L., M. Pilapil, D. Miklos, J. P. Higgins, N. Kambham, Renal Pathology in Hematopoietic Cell Transplantation Recipients (2008) Modern Pathology 21:396-406. (cover illustration)
  • Troxell ML, Masek M, Sibley RK. Immunohistochemical staining of papillary breast lesions. Appl Immunohistochem Mol Morphol. 2007 Jun;15(2):145-53.
  • Troxell, M. L., Bangs, C.D., Lawce, H. J., Galperin, I.B., Baiyee, Robert B. West, R.B., Olson, S. B., Cherry, A. M. Evaluation of Her-2/neu Status in Carcinomas with Amplified Chromosome 17 Centromere Locus. (2006) AJCP. 126:709-16.
  • Troxell, M. L., R. K. Sibley, J. P. Higgins and N. Kambham. Evaluation of C4d Staining in Liver and Small Intestine Allografts. (2006) Archives of Pathology and Laboratory Medicine. 130:1489-96.
  • Troxell, M. L., R. K. Sibley, J. P. Higgins and N. Kambham. Comparison of C4d immunostaining methods in renal allograft biopsies. cJASN. (2006) 1: 583-591.
  • Troxell, M. L., D. Bangs, A. M. Cherry, Y. Natkunam, C. Kong. Cytologic Diagnosis of Burkitt Lymphoma: Role of Ancillary Studies. (2005) Cancer Cytopathology. 105(5):310
  • Troxell, M. L., J. Scandling and R. K. Sibley. Renal Juxtaglomerular Apparatus Hyperplasia. (2005) Nephrology, Dialysis and Transplantation 210(10):2282-3
  • Troxell, M. L., D. J. Loftus, W. J. Nelson, and J. A. Marrs. Mutant cadherin affects epithelial morphogenesis and invasion, but not transformation. (2001) Journal of Cell Science 114: 1237-1246.
  • Troxell, M. L., S. Gopalakrishnan, J. McCormack, B. A. Poteat, J. Pennington, S. M. Garringer, E. E. Schneeberger, W. J. Nelson, and J. A. Marrs. (2000). Inhibiting cadherin function by dominant mutant E-cadherin expression increases the extent of tight junction assembly. Journal of Cell Science 113: 985-996.

Last Updated: 08/09/2010