OHSU Department of Pathology

Antony Bakke, PhD

Scientific Director, Clinical Immunology

Rank: Professor

Clinical Services: Flow Cytometry

Clinical Interests: Immunodeficiency , transplant immunology, autoimmunity

Research Interests: Clinical markers of disease progression Regulatory T cells in combined HCV-HIV infection

Cytometry website

Education:

1971    Washington State University - B.S.
1978    California Institute of Technology, biochemistry - Ph.D.

Training:

1977-79    Research Institute of Scripps Clinic; Cellular and Developmental Immunology
                 -Postdoctoral Fellowship in biochemistry

Boards:

Previous Position:

1980-84 Department of Medicine, University of Southern California, Assistant Professor of Research, Rheumatology

Selected References:

Bakke AC, Purtzer MZ, Ellen E and Deodhar A. Review of CD64 expression and measurement. Clinical and Applied Immunology Reviews. Clinical and Applied Immunology Reviews. 1: 267-275, 2001.
Bakke AC. The Principles of Flow Cytometry. Laboratory Med. 32 (4): 207-211, 2001.
Vandenbark AA, Finn T, Barnes D, Culbertson N, Chou YK, Hicks K, Bakke A, Mass M, Whitham R, and Bourdette D. Diminished frequency of IL-10 secreting, TCR peptide/reactive T cells in multiple sclerosis patients might allow expansion of activated memory T cells bearing the cognate BV gene. J Neurosci Res. 66: 171-176, 2001.
Allen E, Purtzer MZ, Bakke AC and Deodhar A. Neutrophil CD64 Expression: Distinguishing Acute InflammatoryAutoimmune Disease from Systemic Infections. Ann Rheum Dis. 2002;61: 522-525.
Antony C. Bakke PhD. The principles and use of flow cytometry in the clinical laboratory. Tech Sample. Hematology 2002; No. H-6: 27-35.
Rosen HR, Miner C, Sasake AW, Lewinsohn DM, Conrad AJ, Bakke AC, Bouwer HGA, and Hinricks DJ. Frequencies of HCV-specific effector CD4+ T cells by flow cytometry: Correlation with clinical disease stages. Hepatology 2002; 35: 190-198.
Bakke AC, Purtzer MZ, Newton P. The effect of hypnotic-guided imagery on psychological well-being and immune function in patients with prior breast cancer. J Psychosomatic Res. 2002; 53: 1131-37.
Smyk-Pearson SK, Bakke AC, Held PK, Wildin RS. Rescue of the autoimmune scurfy mouse by partial bone marrow transplantation or by injection with T-enriched splenocytes. Clin Exp Immunol. 2003; in press.
Bakke AC, Purtzer MZ, Wildin RS. Immunological studies in a case of attenuated, immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX). Clin Exp Immunol. 2003; in press.

Last Updated: 07/08/2009