Etp1/Etohc1

QTL CodeEtp1/Etohc1 PARC Alias Etp1 MGI AliasEtohc1
Drug Alcohol Phenotype Alcohol Preference Drinking
Assay Consumption of 10% ethanol with two-bottle choice
Chromosome2Peak 28 Range
Max Range (Mb)20.2 - 153.3 Min Range (Mb)37.5 - 130.8 StatusSignificant
LOD score3.8 p value3e-05 Sex Specific
Strains Tested BXDRI, B6D2 F2, STSL Increaser AlleleB6 DominanceAdditive
Comments Mb intervals based on congenics studies
Contact Person T. Phillips Last Updated 2007-04-05 12:28:06

References


Belknap JK, Atkins AL. The replicability of QTLs for murine alcohol preference drinking behavior across eight independent studies. Mamm Genome. 2001 Dec;12(12):893-9.
Medline Link

Phillips TJ, Belknap JK, Buck KJ, Cunningham CL. Genes on mouse chromosomes 2 and 9 determine variation in ethanol consumption. Mamm Genome. 1998 Dec;9(12):936-41.
Medline Link

Belknap JK, Richards SP, O'Toole LA, Helms ML, Phillips TJ. Short-term selective breeding as a tool for QTL mapping: ethanol preference drinking in mice. Behav Genet. 1997 Jan;27(1):55-66.
Medline Link

Phillips TJ, Crabbe JC, Metten P, Belknap JK. Localization of genes affecting alcohol drinking in mice. Alcohol Clin Exp Res. 1994 Aug;18(4):931-41.
Medline Link

Phillips TJ; unpublished data