Calw4

QTL Code Calw4
Chromosome 1 ClassAlcohol
Peak 20 cMPhenotypeChronic Alcohol Withdrawal
Range 12-35 cM AssayArea under the curve for handling-induced convulsions over 25 hr period following 72 hr exposure to ethanol vapor
p Value 0.0001 Strains TestedBXD RI, B6D2 F2
LOD Score 3.1StatusSuggestive

References


Buck KJ, Rademacher BS, Metten P, Crabbe JC. Mapping murine loci for physical dependence on ethanol. Psychopharmacology (Berl). 2002 Apr;160(4):398-407. Epub 2002 Feb 15
Medline Link