Alcdpprov3

QTL CodeAlcdpprov3 PARC Alias Calw5 MGI Alias
Drug Alcohol Phenotype Chronic Alcohol Withdrawal
Assay Area under the curve for handling-induced convulsions over 25 hr period following 72 hr exposure to ethanol vapor
Chromosome4Peak 37 Range30-44
Max Range (Mb) Min Range (Mb) StatusSuggestive
LOD score2.0 p value0.003 Sex Specific
Strains Tested BXD RI, B6D2 F2 Increaser AlleleD2 Dominance
Comments
Contact Person K. Buck Last Updated 2007-04-04 13:22:55

References


Buck KJ, Rademacher BS, Metten P, Crabbe JC. Mapping murine loci for physical dependence on ethanol. Psychopharmacology (Berl). 2002 Apr;160(4):398-407. Epub 2002 Feb 15
Medline Link

Crabbe JC. Provisional mapping of quantitative trait loci for chronic ethanol withdrawal severity in BXD recombinant inbred mice. J Pharmacol Exp Ther. 1998 Jul;286(1):263-71.
Medline Link