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OHSU Division of Hematology and Medical Oncology
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Dedicated to the study and treatment of cancer and disorders of the blood.

 
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Our Faculty

Charles D. Lopez, M.D., Ph.D.
Associate Professor
Fellowship Program Director

Specialty: Tumor Biology and GI Medical Oncology

Clinic Phone: 503-494-6594
Lab Phone: 503-494-2964
E-mail: lopezc@ohsu.edu

 

My major research interest is the laboratory investigation into the basic cellular and molecular mechanisms underlying tumor formation and response to therapy. By studying these complex mechanisms, I ultimately hope to identify molecular targets for novel cancer therapies. My clinical focus is in the area of gastrointestinal oncology and I am actively involved in clinical trials for a variety of GI malignancies.

 
Appointments

  • Associate Professor, Department of Medicine, Hematology/Oncology
  • Associate Professor, Cell & Developmental Biology

 

Professional Education and Training

Education:
  • 1982 B.S., Microbiology, Stanford University.
  • 1990 Ph.D., Endocrinology/Cell Biology, University of California San Francisco.
  • 1991 M.D., University of California San Francisco.
Post-graduate training:
  • 1991-94 Medical Resident, University of California San Francisco Medical Center.
  • 1995-1998 Medical Oncology Fellow, Stanford University Medical Center.
  • 1998-2001 Postdoctoral Fellow, Medical Oncology, Stanford University.
Personal

 
Selected Publications

  • K.M. Kampa, J.D. Acoba, D. Chen, J. Gay, H.J. Lee, K. Beemer, E. Padiernos, N. Boonmark, Z. Zhu, A.C. Fan, A.S. Baily, W.H. Fleming, C. Corless, D.W. Felsher, L. Naumovski, and C.D. Lopez. “Apoptosis Stimulating Protein of p53 (ASPP2) Heterozygous Mice Are Tumor Prone and Have Attenuated Cellular Damage-Response Thresholds.” Proc Natl Acad Sci.  In press (2009).
  • C.D. Blanke, T.M. Beer, K. Todd, M. Mori, M. Stone, and C.D. Lopez.  “Phase II study of calcitriol-enhanced docetaxel in patients with previously untreated metastatic or locally advanced pancreatic cancer.” Invest New Drugs. 2008 Oct 9. [Epub ahead of print]  Read More
  • K. Van Hook, J. Alumkal, and C.D. Lopez. "hADA2a and hADA3: new players in beta-catenin signaling." Cancer Biol Ther. 7(1):129-30 (2008).  Read More