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OHSU Division of Hematology and Medical Oncology
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Dedicated to the study and treatment of cancer and disorders of the blood.

 
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Our Faculty

Elliot Epner, M.D., Ph.D.
Associate Professor of Medicine

Specialty: Lymphoma (Mantle Cell), Transplant

Clinic Phone: 503-494-5058
Office Phone: 503-494-1551
E-mail: epnere@ohsu.edu

 

Dr. Epner received his medical degree in 1983 and Ph.D. in Human Genetics in 1985 from Columbia University. He completed his internships and residency in Internal Medicine at University of California and finished his Fellowship in Medical Oncology at Fred Hutchinson Cancer Center in 1989. From 1989-98 he worked as an attending physician for the Bone Marrow Transplantation Unit, Fred Hutchinson Cancer Center and then moved on to assistant professor of medicine, University Washington. Before coming to OHSU, Dr. Epner worked as an assistant professor of medicine for the Bone Marrow Transplantation Program, University of Arizona Cancer Center. Dr. Epner's clinical focus involves both transplant and nontransplant approaches to the treatment of lymphoma. His research is focused on understanding the genetic events involved in lymphomagenesis, particularly a unique type of NHL, mantle cell lymphoma that involves deregulated expression of the cyclin D1 gene. His laboratory is working on translating this information into new targeted, nontoxic therapies for mantle cell and other lymphomas.

 
Appointments

  • Associate Professor, Department of Medicine, Hematology/Oncology

 

Professional Education and Training

  • 1972-76 Wesleyan University, Middletown, CT (BA Biology)
  • 1976-83 Columbia University, New York, NY (MD)
  • 1983-85 Columbia University New York, NY (PhD Human Genetics)
  • 1983-86 Internship and Residency, Internal Medicine, University of California, Irvine, CA
  • 1986-89 Fellowship, Medical Oncology, Fred Hutchinson Cancer Center, University of Washington, Seattle, WA
Personal

Tennis, Basketball, Soccer.
Other


 
Selected Publications

  • Liu, H, Wang J, and Epner, E. (2004). Cyclin D1 activation in B cell malignancy: association with changes in histone acetylation, DNA methylation and RNA polymerase binding to both promoter and distal sequences. Blood 104:2505-13. Read more
  • Wang J, Liu H, Lin CM, Aladjem MI, Epner EM. Targeted deletion of the chicken beta -globin regulatory elements reveals a cooperative gene silencing activity. J Biol Chem. 2005 Apr 11; [Epub]. Read more
  • Epner,E., Reik, A., Cimbora, D., Telling, A., Fiering, S., Keller,G., and Groudine, M. (1998). The -Globin LCR is not Required for an Open Chromatin Structure or Low Level Transcription of the Mouse -Globin Locus. Molecular Cell, 2:447-455.
  • Kerbauy, F, Storb, R, Hegenbart, U, Gooley, T, Shizuru, J, Al-Ali, H, Radich, J, Maloney, D, Agura, E, Bruno, B, Epner,Chauncey, T, Blume, K, Niederweiser, D, and Sandmaier, B Chauncey, T, Blume, K, Niederweiser, D, and Sandmaier, B. (2005). Hematopoietic cell transplantation from HLA-identical sibling donors after low-dose radiation-based conditioning for treatment of CML. Leukemia Mar 31; [Epub]. Read more
  • Hegenbart, U, Niederwieser, D, Forman, S, Holler, E, Leiblein, S, Johnston, L, Ponisch, W, Epner, E, Witherspoon, R, Blume, K, and Storb, R. (2003). Hematopoietic cell transplantation from related and unrelated donors after minimal conditioning as a curative treatment for severe paroxysmal nocturnal hemoglobinuria. Biology of Blood and Marrow Transplantation 9:689-97.

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