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| Meet the Staff
Dr. Marka Crittenden, MD, PhD
AM Board of Radiology Homan Pathway
Publications:
(2005) 'Gene therapy to manipulate effector T cell trafficking to tumors for immunotherapy'. Gough MJ, Crittenden MR, Thanarajasingham U, Sanchez-Perez L, Thompson J, Jevremovic D, Vile RG. J Immunol 174: 5766-73
(2005) 'Intratumoral Immunotherapy: strategies that use the tumor site to enhance anti-tumor immunity'[Review]. Crittenden MR, Thanarajasingham U, Vile RG, Gough MJ. Immunology 114: 11-22
(2004) 'MIP-3 alpha Transfection into a Rodent Tumor Cell Line Increases Intratumoral Dendritic Cell Infiltration but Enhances (Facilitates) Tumor Growth and Decreases Immunogenicity'. Bonnotte B, Crittenden M, Larmonier N, Gough M, Vile RG J Immunol 173: 4929-4935
(2004) 'Induction of cell stress through gene transfer of an engineered heat shock transcription factor enhances tumor immunogenicity'. Gough MJ, Melcher AA, Crittenden MR, Sanchez L, Voellmy R, Vile RG Gene Therapy 11(13): 1099-1104
(2003) 'Expression of Inflammatory Chemokines Combined with Local Tumor Destruction Enhances Tumor Regression and Long Term Immunity'. Crittenden MR, Gough MJ, Harrington K, Olivier K, Thompson J, & Vile RG Cancer Research. 63: 5505-12
(2003) 'Pharmacologically regulated production of targeted retrovirus from T cells for systemic anti-tumor gene therapy'. Crittenden MR, Gough MJ, Chester J, Kottke T, Thompson J, Ruchatz A, Clackson T, Luic Cosset F, Chong H, Diaz R-M, Harrington K, Alvarez Vallina L & Vile RG. Cancer Research. 63: 3173-80
(2002) 'Cells as vehicles for cancer gene therapy: the missing link between targeted vectors and systemic delivery? Human Gene Therapy'. Harrington K, Alvarez-Vallina L, Crittenden M, Gough M, Chong H, Diaz RM, Vassaux G, Lemoine N, Vile R 13(11): 1263-80
(2002) 'Tumor antigen-specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor-modified T cells'. Chester J, Ruchatz A, Gough M, Crittenden M, Chong H, Loic-Cosset F, Diaz RM, Harrington K, Alvarez-Vallina L, Vile R. Nature Biotechnology 20: 256-63
(2001) 'Macrophages orchestrate the immune response to tumor cell death'. Gough MJ, Melcher AA, Ahmed A, Crittenden MR, Riddle DS, Linardakis E, Ruchatz AN, Emiliusen LM & Vile RG. Cancer Research 61(19): 7240-7
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Dr. Marka Crittenden,
MD, PhD
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