Neurobiology of Disease

 


 
 
 
Date: May 31, 2012 (Thursday)
Time: 10 a.m.
Theme: Injury and Repair (Multiple Sclerosis)
Module: Overview
Session: Axonal regeneration
Instructor: Gary Westbrook, Senior Scientist, Vollum Institute; Professor, Neurology, OHSU
Objectives: This session will discuss the potential and limits to axonal regeneration. This will be a journal club format so come prepared to discuss the readings.
Study questions:
  1. What are the classes of inhibitory factors that limit regeneration?
  2. How does Notch inhibit regeneration in the Bejjani and Hammarlund?
  3. How do these authors block Notch?
 
Readings:
  1. Giger et al., CSH Perspect Biol 1-21, 2010
    Adobe Acrobat
  2. Bejjani Neuron 73, 268-278, 2012.
    Adobe Acrobat
Video:
  1. http://www.ohsu.edu/edcomm/flash/flash_player.php?params=4%60/sch/neus/626-053112.flv%60vod&width=640&height=480&title=NEUS%20626%2C%205/31/12