Neurobiology of Disease


Date: May 31, 2012 (Thursday)
Time: 10 a.m.
Theme: Injury and Repair (Multiple Sclerosis)
Module: Overview
Session: Axonal regeneration
Instructor: Gary Westbrook, Senior Scientist, Vollum Institute; Professor, Neurology, OHSU
Objectives: This session will discuss the potential and limits to axonal regeneration. This will be a journal club format so come prepared to discuss the readings.
Study questions:
  1. What are the classes of inhibitory factors that limit regeneration?
  2. How does Notch inhibit regeneration in the Bejjani and Hammarlund?
  3. How do these authors block Notch?
  1. Giger et al., CSH Perspect Biol 1-21, 2010
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  2. Bejjani Neuron 73, 268-278, 2012.
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