Neurobiology of Disease


Date: May 29, 2012 (Tuesday)
Time: 10 a.m.
Theme: Injury and Repair (Multiple Sclerosis)
Module: Overview
Session: Axonal injury and repair
Instructor: Mary Logan, Jungers Center; Assistant Professor, Neurology
Objectives: This first part of the session will overview the nervous system response to axonal injury, followed by a student-led discussion of a recent paper.
Study questions:
  1. List Coleman's categories of disruption of axonal transport.
  2. What classes of molecules/functions are needed for axons to survive?
  3. How long does it take cargo to go from soma to axon terminal in the longest human axons using 'fast' axonal transport?
  1. Coleman Adv Genet 73, 185-217, 2011
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  2. Avery et al, Curr Biol 22, 596-600, 2012.
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