Neurobiology of Disease


Date: April 17, 2012 (Tuesday)
Time: 10 a.m.
Theme: Neurodegeneration (Alzheimer's, Parkinson's disease)
Module: Overview
Session: The changing face of Alzheimer's disease: From early onset families in Colombia to rethinking the basics.
Instructor: Kenneth Kosik, Professor of Neuroscience, UC Santa Barbara
Objectives: Dr. Kosik has worked with an extended family in Colombia that has early onset Alzheimer's disease. He will review his experience in working with this project and its implications for understanding the mechanisms of AD.
Study questions:
  1. What is the genetic mutation in the Colombian family?
  2. What can the early forms of AD tell us about the sporadic form?
  1. Colombian family NOD2012
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  2. Lopera et al., JAMA 277, 793-799, 1997.
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