Neurobiology of Disease


Date: May 10, 2010 (Monday)
Time: 10:30 a.m.
Theme: Neuronal-Glial Interactions (Multiple Sclerosis)
Module: Overview
Session: MS and demyelinating disease
Instructor: Dennis Bourdette
Description: This session will overview the clinical spectrum of demyelinating disease (principally MS in this discussion) and highlight some of the key issues in the neurobiology and approaches to treatment.
Study questions:
  1. What are the essential components of making a clinical diagnosis of MS?
  2. What aspects of MS are most affected by beta interferon and copolymer-1?
  3. What current treatments address myelin repair or neurodegeneration in MS?
  1. Weiner HL (2009) The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease? Ann Neurol 65:239-248.
    Adobe Acrobat
  2. Quarles RH, Morell P, McFarland HF (2006) Diseases involving myelin. In Basic Neurochemistry, 7th Ed. (GJ Siegel, RW Albers, ST Brady, DL Price, eds.), Elsevier Academic Press, 639-652.
    Adobe Acrobat