Neurobiology of Disease

 


 
 
 
Date: April 19, 2010 (Monday)
Time: 10:30 a.m.
Theme: Neurodegeneration (Alzheimer's, Parkinson's Disease and Aging)
Module: ToolBox
Session: Clinical Trials
Instructor: Penny Hogarth
Description: This session will provide a practical introduction to how clinical trials are designed, staged (Phase 1-3, etc.) and conducted.
Study questions:
  1. Describe the purpose of randomization and the use of "double-blind controls".
  2. What's the advantage of a cross-over trial design?
  3. Describe some of the factors in selecting the best "outcome variable" for a clinical trial.
 
Readings:
  1. Marshall FJ, Kieburtz K, McDermott M, et al (1996) Clinical research in neurology. From observation to experimentation. Neurol Clin 14:451-466.
    Adobe Acrobat
Video:
  1. http://www.ohsu.edu/edcomm/flash/flash_player.php?params=4%60/sch/neus/626-041910.flv%60vod&width=640&height=480&title=NEUS%20626%2004-19-10