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| May 29, 2009 (Friday) |
| 10:30 a.m. |
| Dopamine systems - movement and reward (PD and substance abuse) |
| Overview |
| Maladaptive plasticity and addiction |
| John Williams |
| This session will discuss the maladaptive changes in the normal reward pathways that
contribute to addiction and substance abuse. |
- Is dopamine addictive?
- Why might exogenous dopamine be more active on limbic pathways than motor pathways in Parkinson's disease?
- Is dopamine an absolute requirement for all reward learning?
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- Dagher A, Robbins TW (2009). Personality, addiction, dopamine: insights from Parkinson's disease.
Neuron 61:502-508.
- Kreitzer AC, Malenka RC (2008). Striatal plasticity and basal ganglia circuit function.
Neuron 60:543-554. (optional)
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