Neurobiology of Disease


Date: May 18, 2009 (Monday)
Time: 10:30 a.m.
Theme: Dopamine systems - movement and reward (PD and substance abuse)
Module: Overview
Session: Overview of Parkinson's Disease
Instructor: Jay Nutt
Description: This session will overview the clinical features of PD and highlight some of the recent directions in pathogenesis and treatment options.
Study questions:
  1. What can causes parkinsonism other than the most common "idiopathic" or "sporadic" type?
  2. What are the molecular components of "Lewy" bodies?
  3. What is the rationale for "neuroprotective" studies and have these been successful?
  1. Nutt JG, Wooten GF (2005). Diagnosis and initial management of Parkinson's disease. N Engl J Med 353:1021-1027.
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  2. Wichmann T, DeLong MR (2006). Neurotransmitters and disorders of the basal ganglia. In Basic Neurochemistry, 7th Ed., (GJ Siegel, RW Albers, ST Brady, DL Price, eds.), Elsevier Academic Press, 761-771.
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