| April 24, 2009 (Friday) |
| 10:30 a.m. |
| Neurodegeneration (ALS and Alzheimer's) |
| Overview |
| Abeta and tau in the pathogenesis of Alzheimer's disease: whether, when and how to treat. |
| David Holtzman (visiting faculty) |
| David Holtzman, an expert on Alzheimer's disease will provide us with an update on
treatment strategies for Alzheimer's. |
- If there was an effective immunotherapy for Alzheimer's, at what stage of the disease would you want to treat?
- If your answer to #1 is early, what special problems does that create?
- How dependent is the success of immunotherapy on knowing the mechanism of action of the target, e.g. Abeta or tau?
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- Brody DL, Holtzman DM (2008). Active and passive immunotherapy for neurodegenerative disorders.
Annu Rev Neurosci 31:175-193.

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- http://media/ohsu.edu/ramgen/sch/ogi/neus/626-042409.rm
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