| April 1, 2009 (Wednesday) |
| 10:30 a.m. |
| Introduction |
| ToolBox |
| Clinical information gathering |
| Joe Quinn/Gary Westbrook |
| Physicians in the clinic diagnose neurological and psychiatric diseases largely based on the
patient's clinical history and physical examination. Laboratory tests are often unhelpful or simply
confirmatory. In this session, we will discuss how clinicians assess the nervous system and the diagnostic
steps necessary to define the part of the nervous system affected (AKA "where's the lesion") and then
determine the underlying pathological process. This exercise will be used to compare clinical and research
criteria for neuropsychiatric disease, and how that impacts studies of underlying mechanisms and potential
therapies. We will use clinical vignettes of memory loss and weakness as part of the discussion. |
- Neurologists often approach clinical problems by trying to determine "where's the lesion?". What does this mean?
- What components of nervous system function can be assessed in the neurological exam?
- How would you define a "disease" for the purposes of a experimental protocol or clinical trial?
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- Groopman J (2007). What's the trouble? New Yorker 82:36-41.
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| http://media.ohsu.edu/ramgen/sch/ogi/neus/626-040109.rm |