Neurobiology of Disease

 


 
 
 
Date: April 21, 2008 (Monday)
Time: 10 a.m.
Theme: Regeneration and repair: brain and spinal cord trauma
Module: Overview
Session: Mechanisms of traumatic brain injury
Instructor: Povlishock (Visiting faculty)
Description: Motor vehicle accidents, diving accidents, gunshot wounds, concussive injuries from roadside bombs all can result in devastating trauma to the brain and spinal cord. This 5-session theme will examine some of the acute and chronic clinical manifestations, and discuss some of the underlying mechanisms. In this first session, John Povlishock from the Medical College of Virginia (Richmond, VA), an expert on traumatic brain injury, will provide an overview of the types of brain injury and how proposed mechanisms can be examined.
 
Readings:
  1. Cernak I (2005). Animal models of head trauma. NeuroRx 2,410-422.
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  2. Farkas O and Povlishock JT (2007). Cellular and subcellular change evoked by diffuse traumatic brain injury: a complex web of change extending far beyond focal damage. Prog Brain Res. 161, 43-59.
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Video:
  1. 042108 NEUS 626: http://media.ohsu.edu/ramgen/sch/ogi/neus/626-042108.rm