Neurobiology of Disease

 


 
 
 
Date: May 30, 2007 (Wednesday)
Time: 10 a.m.
Theme: Neuroregeneration and repair: MS
Module: Overview
Session: The immunology of demyelinating disease and the EAE model
Instructor: Vandenbark
Description: This session will examine the basis for the immune hypothesis of demyelinating disease, and its implications for understanding the disease process and designing therapies.
 
Readings: Experimental Allergic Encephalomyelitis: A Misleading Model of Multiple Sclerosis
Ann Neurol 2005;58:939-945
© 2005 American Neurological Association

[ Download ]

How to Successfully Apply Animal Studies in Experimental Allergic Encephalomyelitis to Research on Multiple Sclerosis
Ann Neurol 2006;60:12-21
© 2006 American Neurological Association

[ Download ]

 
Additional Readings: Encephalitogenic potential of the myelin basic proteinpeptide (amino acids 83-99) in multiple sclerosis: Results of aphase II clinical trial with an altered peptide ligand
NATURE MEDICINE • VOLUME 6 • NUMBER 10 • OCTOBER 2000
© 2000 Nature America Inc.

[ Download ]

Expansion and Functional Relevance of High-Avidity Myelin-Specific CD4+ T Cells in Multiple Sclerosis
The Journal of Immunology
Copyright © 2004 by The American Association of Immunologists, Inc.

[ Download ]

[ Video ]