Neurobiology of Disease

 


 
 
 
Date: April 18, 2007 (Wednesday)
Time: 10 a.m.
Theme: Genes and Disease
Module: Overview
Session: Journal Club
Instructor: Westbrook
Description: Even single gene mutations can cause multiple clinical seizure presentations. In a journal club format, we will examine a specific epilepsy gene mutation and examine its molecular and cellular phenotype and how that relates to the clinical presentation.
 
Readings:

There will not be an in-class session on April 18. Please read the article and prepare a 1-page summary of the main findings, strengths and weaknesses of the work and its significance. These should be handed in no later than Monday April 23. You may work/discuss the article together, but your summary should be in your own words.

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy
VOLUME 9 | NUMBER 9 | SEPTEMBER 2006 NATURE NEUROSCIENCE
© 2006 Nature Publishing Group

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Additional Readings:  

Last modified on 04/17/2007 by rdaweb@ohsu.edu