Dr. Yang received his Medical Degree, did his internship
and residency in Nephrology in China. He completed post-doctoral training
with Dr. Peter Aronson in the Section of Nephrology at Yale University
School of Medicine from 1994-1998. He joined the research faculty
of the Division of Nephrology & Hypertension in OHSU in 2001.
His research work currently focuses on the mechanisms by which WNK
kinases modulate renal transporters and how mutations of WNK kinases
cause human hypertension.
M.D. - Medicine, 1983 China
Nephrology - 1983-1988 China
Kidney salt transport and hypertension.
- Yang Cl, Angell J, Mitchell R and Elliosn DH: WNK kinase regulate
thiazide-sensitive Na-Cl cotransport. J Clin Invest. 2003 Apr; 111(7):1039-45.
- Knauf F, Yang CL, Thomson RB, Mentone SA, Giebisch G, Aronson
PS. Identification of a chloride-formate exchanger expressed on
the brush border membrane of renal proximal tubule cells. Proc Natl
Acad Sci U S A. 2001 Jul 31;98(16):9425-30. Epub 2001 Jul 17. PubMed
- Wang T, Yang CL, Abbiati T, Schultheis PJ, Shull GE, Giebisch
G, Aronson PS. Mechanism of proximal tubule bicarbonate absorption
in NHE3 null mice. Am J Physiol. 1999 Aug; 277(2 Pt 2):F298-302.
- Cox, GA, Lutz CM, Yang CL, et al. Sodium/Hydrogen exchanger gene
defect in slow-wave epilepsy mutant mice. Cell 91:139-148,1997.
- Du XH, Yang CL. Mechanism of gentamicin nephrotoxicity in rats
and protective effective of zinc-induced metallothionein synthesis.
Nephrol Dial Transplant 9 Suppl 4:135-1340, 1994. PubMed