Dr. Wahba is a graduate of the OHSU Nephrology Fellowship Program and was appointed as an Instructor of Medicine in Nephrology July 1, 1999. He was promoted to Assistant Professor of Medicine in March 2001. He received a National Kidney Foundation research fellowship award in 1998. During his training, his research focus was the mechanisms of immunosuppressive nephrotoxicity and cell death as it relates to the renin-angiotensin system.
Dr. Wahba’s current focus is clinical nephrology, teaching, and clinical research. He has a particular interest in bedside teaching and using physical examination skills in clinical problem solving in nephrology. He received the house staff teaching award in 2003. His clinical research interests include vascular access related complications including infection and dysfunction, acute renal failure, obesity-related renal dysfunction, and metabolic bone disease in dialysis-treated patients.

Degrees:

M.B.B.Ch. - Faculty of Medicine, Cairo University, 1991

Residency:

Internal Medicine - Cairo University, Cairo, Egypt
Harbor Hospital Center, Baltimore, Maryland, 1994 - 1996
Chief Resident 1997 - Harbor Hospital Center

Fellowship:

Nephrology - Oregon Health & Science University, 1997 - 1999

Research Interest:

Immunosuppressive nephrotoxicity, Programmed cell death in renal disease, Vascular access infection and dysfunction, Acute renal failure, Obesity-related renal disease

Clinical Interest:

Calcineurin inhibitor nephrotoxicity and general nephrology including glomerular diseases, acid-base disorders, fluid and electrolyte disorders, acute renal failure, dialysis, and renal osteodystrophy

Representative Publications:

• Yang CW, Faulkner GR, Wahba IM, Christiansen TA, Bagby GC, Jin DC, Abboud HE, Andoh TF, Bennett WM. Expression of apoptosis?related genes in chronic cyclosporine nephrotoxicity in mice. Am J Transplant 2:391-399, 2002
• Deodhar A, Allen E, Daoud K, Wahba IM.. Vasculitis secondary to Staphylococcal protein A immunoadsorption column treatment in rheumatoid arthritis. Semin Arthritis Rheum 32:3-9, 2002
• Wahba IM, Bennett WM. Nephrotoxicity of drugs used in rheumatology: Nephrotoxicity of calcineurin inhibitors. In: Adu D, Emery P and Madaio M (eds): Rheumatology and the Kidney, Oxford University Press, NY, pp 397-414, 2001
• Wahba IW. Tubulointerstitial Nephropathies. In: Bennett WM (ed): Treatment Strategies in Nephrology and Hypertension, PocketMedicine.com, 2003
• Wahba IW. Secondary involvement of the kidney in neoplastic diseases and genitourinary malignancies. In: Bennett WM (ed): Treatment Strategies in Nephrology and Hypertension, PocketMedicine.com, 2003
• Yang CW, Wahba IM, Faulkner GR, Andoh TF, Bagby GC, Bennett WM. Imbalance of Bcl-2 family genes and upregulation of p53 are associated with apoptotic cell death in chronic cyclosporine nephrotoxicity. Transplantation 67:S38, 1999
• Wahba IM, Yang CW, Abboud HE, Eakes A, Bennett WM, Andoh TF. Angiotensin II receptor type I blockade reduces cyclosporine A nephropathy via downregulation of apoptotic genes in viv0. J Am Soc Nephrol 10:653A, 1999
• Olyaei AJ, Wahba IM, Norman DJ, Barry JM, Bennett WM, de Mattos AM. Incidence of CMV disease beyond 90 days after ganciclovir prophylaxis: results from a cohort of high-risk renal transplant recipients. J Am Soc Nephrol 10:763A, 1999
• Andoh TF, Wahba IM, Bennett WM. Effect of sirolimus on renal function and morphology in post-ischemic rat kidney. J Am Soc Nephrol 11:658A, 2000
• Wahba IM, Andoh TF and Bennett WM. The major apoptotic pathways in chronic cyclosporine nephropathy are regulated by angiotensin II. Am J Kidney Dis, 37:A34, 2001
• Andoh TF, Wahba IM, Choi SO, Bennett WM. Comparison of sirolimus and mycophenolate mofetil on renal function and morphology in post-ischemic rat kidney. Transplantation 2001
• Wahba IM, Choi SO, Andoh TF, Bennett WM. In vivo activation of the major apoptotic pathways precedes fibrosis in chronic cyclosporine nephropathy. J Am Soc Nephrol 12:807A, 2001
• Andoh TF, Choi SO, Wahba IM, Bennett WM. Mycophenolate mofetil modifies the effects of sirolimus on impaired recovery from renal ischemia in rats. J Am Soc Nephrol 12:851A, 2001
• Shibagaki Y, Tai C, Nayak A, Wahba IM. Abdominal compartment syndrome: A common cause of acute renal failure? Am J Kidney Dis 41:A34, 2003