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Trigeminal Neuralgia: Medical Treatment

  • No Treatment - Symptoms may subside/disappear without treatment.

  • Anticonvulsant drugs - e.g. Tegretol (carbamazepine) or Neurontin (gabapentin), Trileptal (oxcarbazepine), Dilantin (phenytoin), Depakote (sodium valporate) . This common treatment works by keeping the trigeminal nerve from “firing” or “going off”.

  • Antispastic agents - e.g. Lioresal (baclofen). These can be used if a patient develops an adverse side effect to anticonvulsant drugs. Not as effective as an oral anticonvulsant.

  • Benzopiazepines - e.g. Klonopin (clonazepam). These can be used if a patient develops an adverse side effect to anticonvulsant drugs. Not as effective as an oral anticonvulsant.

  • Antidepressant drugs - e.g. amitriptyline, tricyclic antidepressants. Some antidepressant drugs also have significant pain relieving effects. Not as effective as an oral anticonvulsant.

  • Opioids - short-term use only, especially in critical cases. Trigeminal neuralgia is classically resistant to opioids. Not as effective as an oral anticonvulsant.

  • Alternative medical therapies - Some patients report having reduced or relieved pain by means of alternative medical therapies such as acupuncture, chiropractic adjustment, self-hypnosis or meditation. Results are not long-lasting or a definitive solution to the problem.

 

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