Succinylacetone With Organic Acids, Urine

OHSU Service Code:

067-6332

CPT Codes:

82541

Lab Section:

Biochemical Genetics

Specimen
Requirements:

SAMPLE MUST BE FROZEN STAT AND DELIVERED FROZEN.
2-6 mL aliquot of urine, preferably obtained during acidosis or after overnight fast; deliver within 2 hr on ice or freeze and transport frozen.
MUST PROVIDE CLINICAL INDICATION AND COMPLETE LIST OF MEDICATIONS. ANTIBIOTICS, VITAMINS, SPECIFIC DIET OR FORMULA, ETC. If patient has intermittent symptoms, sample should be obtained when patient is symptomatic.
For requisition slips.

Pediatric Specimen
Requirements:

3 mL urine in a urine sample cup. Freeze immediately.

Comments:

Indication: For diagnosis of tyrosinemia type I, when tyrosine metabolites are present. Succinylacetone is quantitated by stable isotope dilution GC/MS in an additional run after organic acid analysis.