- OHSU Service Code:
- 102-7147
- Lab Section:
- Molecular Diagnostic Center
- Synonyms:
- ET (Essential Thrombocythemia); IMF (Ideopathic Myelofibrosis); PV (Polycythemia)
- Specimen
Requirements:
- 6 mL peripheral blood, LAVENDER top tube or ACD (A or B) vacutainer tube. For requsition slips.
- Reference Range:
- Reportable Range:
Presence or absence of the point mutation.
For additional information.
- Comments:
- PCR-based testing to detect an acquired single point mutation (Val 617 Phe) in the JAK2 kinase auto-inhibitory domain. The presence of the point mutation has been associated with different myeloproliferative diseases including polycythemia vera (PV), essential thrombocythemia (ET) and ideopathic myelofibrosis (IMF).
