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Maternal Cell Contamination Testing

OHSU Service Code:
102-8907
Lab Section:
Molecular Diagnostic Center
Synonyms:
Maternal Cell Rule-Out
Specimen
Requirements:
Mother: 6.0 mL blood in EDTA vacutainer tube.
Fetus: 10 mL amniotic fluid; 10-20 mg chorionic villus (CVS) or 2 T-25 flasks of cultured amniocytes or CVS. For requisition slips.
Comments:
PCR based testing of the fetal specimen to detect the presence of contaminating maternal DNA. The sensitivity of the assay could detect approximately 5% maternal material in the fetal specimen. Maternal contamination studies are performed as confirmatory tests for genetic diease testing of fetal material.