OHSU Bioinformatics and Biostatistics Core GMSR
  You are here: Home MIAME BBC Supporting Materials for Stenzel-Poore

Navigation Ischemic preconditioning in the brain reprograms the genetic response to cerebral ischemia and mimics neuroprotective strategies reported to occur in hibernation.

MIAME

Microarray Resources
(under construction)

 

BBC MIAME Supporting Materials


Ischemic preconditioning in the brain reprograms the genetic response to cerebral ischemia and mimics neuroprotective strategies reported to occur in hibernation.

Mary P. Stenzel-Poore1, Susan L. Stevens1, Zhigang Xiong5, Nikola S. Lessov2, Christina A. Harrington3, Motomi Mori4, Robert Meller5, Holly L. Rosenzweig1, Eric Tobar1, Tatyana E. Shaw1, Xiangping Chu5 and Roger P. Simon5

1Department of Molecular Microbiology and Immunology, 2Oregon Stroke Center, 3Vaccine and Gene Therapy Institute, 4Biostatistics & Bioinformatics Shared Resource Cancer Institute, Oregon Health & Science University, Portland, Oregon; 5Robert S. Dow Neurobiology Laboratories, Legacy Research, Portland, Oregon.

Supporting Materials:
Miame Checklist: BBC Miame Checklist (PDF format)
Raw Data from Affymetrix MAS 4.0: Comparisons and Absolute Analysis
Data Analysis: ANOVA and t-test Results
Final List: Final Gene List Genes that met the following criteria:

  1. A 2.2 fold difference of expression in the ipsilateral hemisphere as compared to the contralateral hemisphere in at least 2 of the 3 pools of RNA.
  2. A P value of less than 0.05 using a t-test comparing differences between hemispheres.
    A gene was considered differentially regulated if both conditions were met.



Oregon Health & Science University