Prehospital Resuscitation IMpedance valve and Early vs Delayed analysis (ROC PRIMED) Trial

Note: This study was completed on November 6, 2009
For more information about the completion of the study,
please read the official OHSU press release
and the NIH press release here

Cardiac arrest is the sudden, abrupt loss of heart function. Death usually occurs within minutes unless cardiopulmonary resuscitation (CPR), rapid defibrillation, and paramedic interventions are available. CPR consists of pumping on the patient's chest and delivering breaths to produce some circulation until the heart can be restarted. When the chest is compressed, oxygen-rich blood is pumped forward. When the chest is released, oxygen-poor blood is brought back to the heart and lungs where it can be restored with oxygen before being pushed out to the body with another compression. Both actions -- pushing oxygen-rich blood forward and bringing oxygen-poor blood back to the heart and lungs -- are important. CPR however produces only about 30% of normal circulation. Methods to improve the circulation produced by CPR may lead to better survival.

ROC Primed - Page 1   |   Page 2   |   Page 3

Study Results

Results were published in the New England Journal of Medicine on September 1, 2011.

Cardiac Arrest and the Limitations of Clinical Trials
Read the Editorial

A Trial of an Impedance Threshold Device in Out-of-Hospital Cardiac Arrest
Read the Article

Early versus Later Rhythm Analysis in Patients with Out-of-Hospital Cardiac Arrest
Read the Article