OHSU

ROC

The Resuscitation Outcomes Consortium (ROC) was created to learn which treatments work when people have a cardiac arrest or severe injury. The ROC consists of ten sites and a coordinating center. The ROC investigators work with Emergency Medical Services (EMS) systems at each site to do these studies. Treatments studied include promising resuscitation drugs, tools and techniques.

What Is ROC?

ROC Logo

The Resuscitation Outcomes Consortium (ROC) was created to learn which treatments work when people have a cardiac arrest or severe injury. The ROC consists of ten sites and a coordinating center. The ROC investigators work with Emergency Medical Services (EMS) systems and local hospitals at each site to do these studies. Treatments studied include promising resuscitation drugs, tools and techniques.

The ROC Investigators do studies in which people who qualify receive either the currently accepted treatment or a new treatment assigned by chance (that is, in a manner like a coin toss). The trials are designed to test promising new treatments so that EMS providers can use those treatments most likely to benefit the public.

Read the News Article

Further Information:

Recently Closed Study

ROC PRIMED
(Prehospital Resuscitation using an IMpedance valve and Early vs Delayed analysis)
Note: This study was closed on November 6, 2009.
For more information, please read the official OHSU press release.

Cardiac arrest is the sudden, abrupt loss of heart function. Death usually occurs within minutes unless cardiopulmonary resuscitation (CPR), rapid defibrillation, and paramedic interventions are available. CPR consists of pumping on the patient's chest and delivering breaths to produce some circulation until the heart can be restarted. When the chest is compressed, oxygen-rich blood is pumped forward. When the chest is released, oxygen-poor blood is brought back to the heart and lungs where it can be restored with oxygen before being pushed out to the body with another compression. Both actions -- pushing oxygen-rich blood forward and bringing oxygen-poor blood back to the heart and lungs -- are important. CPR however produces only about 30% of normal circulation. Methods to improve the circulation produced by CPR may lead to better survival.

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Current Studies

ALPS
Amiodarone, Lidocaine, Placebo Study

Read the official NIH Press release. Learn More

HypoResus
Hypotensive Resuscitation versus Standard Resuscitation Study

Learn More

PREVIOUS STUDIES

ROC-PRIMED

NHLBI Stops Enrollment in Study on Resuscitation Methods for Cardiac Arrest - November 6, 2009

For more information about the closure of the study, please read the official OHSU press release
and the NIH press release.


Hypertonic Saline Study

10/11/2010- Results published in JAMA.
View the article and results.

05/12/2009 - Hypertonic Saline in Traumatic Brain Injury study stopped

For more information about the closure of the study see the NIH press release
or www.clinicaltrials.gov

For more information about traumatic brain injury, visit the website: National Institute of Neurological Disorders and Stroke - Traumatic Brain Injury: Hope Through Research

Hypertonic Saline in Trauma Patients in Shock-stopped - March 26, 2009

For more information about the closure of the HS shock study see the
NIH press release
or visit www.clinicaltrials.gov