Resuscitation Outcomes Consortium

What Is ROC?

ROC Logo

The Resuscitation Outcomes Consortium (ROC) was created to learn which treatments work when people have a cardiac arrest or severe injury. The ROC consists of ten sites and a coordinating center. The ROC investigators work with Emergency Medical Services (EMS) systems and local hospitals at each site to do these studies. Treatments studied include promising resuscitation drugs, tools and techniques.

The ROC Investigators do studies in which people who qualify receive either the currently accepted treatment or a new treatment assigned by chance (that is, in a manner like a coin toss). The trials are designed to test promising new treatments so that EMS providers can use those treatments most likely to benefit the public.

Further Information:

Current Studies

Tranexamic Acid for Traumatic Brain Injury (TXA)

Enrollment Began May 26, 2015

Oregon Health & Science University is part of a multi-site study testing whether people who have life threatening or life altering traumatic brain injury do better when they receive a medication called Tranexamic Acid (TXA) that is used to stabilize bleeding in the body. The study will be conducted at 10 Level 1 trauma centers in North America including OHSU. The research team will look at the results to determine if the study medication, TXA, given as soon as possible after injury improves the mental recovery after traumatic brain injury.

Learn More about TXA

Pragmatic Airway Resuscitation Trial (PART)

Enrollment began on March 29th, 2016

Learn More about PART

Recently Closed Studies

Amiodarone, Lidocaine, Placebo Study (ALPS)

Enrollment Closed October 24, 2015
Read the official NIH Press release.
Read the OHSU Press release.

Learn More about ALPS