Toxicology Fellowship

Session Topics and Chapter Lists

July and August - Core Toxicology Session Topics

July and August - Core Toxicology Session Topics

Acute Care Core Toxicology:
  • GI decontamination - gastric emptying (ipecac and lavage)
  • GI decontamination - activated charcoal
  • GI decontamination - whole bowel irrigation
  • Acetaminophen / NAC
  • Salicylates and NSAIDs / sodium bicarbonate
  • Toxic Alcohols / fomepizole
  • Beta Blockers / glucagon / CCB /High dose insulin
  • Antipsychotics
  • Carbon monoxide / HBO
  • Cyclic antidepressants / sodium bicarbonate
  • Atypical antidepressants, SRIs
  • Sedative/hypnotics / flumazenil / GHB
  • Withdrawal principles and ethanol withdrawal (2 chapt)
  • Lithium and Monoamine oxidase inhibitors (2 chapt)
  • Cardioactive steroids / digoxin-specific antibodies
  • Antiepilectics and L-carnitine
  • Opioids / Naloxone
  • Electrophysiologic and electocardiographic principles and cardiologic principles II: hemodynamics
  • Snake envenomation / crotalid anti-venom
  • Iron / deferoxamine
  • Antidysrhythmics
  • Marijuana/Cannabinoids
  • Methamphetamine and amphetamines
  • Nicotine
  • Antihistamines / physostigmine

Laboratory principles in Goldfrank = preparation for the lab lecture series

Wastewater treatment facilities (SK 51) = prep for wastewater plant tour

Wednesday Conferences (1st)

Wednesday Conferences

1st Wednesday - Neurotransmitters and core Tox principles
  • Neurotransmitters and neuromodulators(GF 14)
    • Acetylcholine, muscarinic/nicotinic receptors, norepinephrine/epinephrine, alpha/beta receptors
  • Neurotransmitters and neuromodulators(GF 14)
    • Dopamine and dopamine receptors
    • Serotonin and 5HT receptors
    • GABA and GABA channel
  • Neurotransmitters and neuromodulators(GF 14)
    • GHB
    • Glycine and Adenosine
    • Glutamate and NMDA receptor
  • Cyanide / hydrogen sulfide / cyanide antidotes
  • Mushrooms / silibinin
  • Insecticides: Organic phosphorous / carbamate / atropine / 2-pam / organic chlorines / pyrethrins/pyrethroids / insect repellents
  • Cocaine / internal concealment of xenobiotics
  • Hallucinogens
  • Phencyclidine and ketamine
  • Lead / BAL / EDTA
  • Mercury
  • Arsenic / DMSA
  • Caustic ingestions
  • Antiseptics, disinfectants, and sterilants
  • Hydrocarbons
  • Hazardous materials incident response
  • Inhalants
  • Fumigants (SK100)
  • Fungicides (SK102)
  • Herbicides

Wednesday Conferences (2nd)

Wednesday Conferences

2nd Wednesday Core - pharmaceuticals / drugs - Chapters are chosen from Toxicologic Emergencies (Goldfrank LR, et al)
  • Antimalarials and antituberculous drugs(2 chapt) / pyridoxine
  • Antibiotics, antifungals, antivirals
  • Anti-migraine medications
  • Methylxanthines
  • Antihypertensives (ACE, ARB, vasodilators, alpha agents)
  • Antidiabetics and hypoglycemic (Insulin and sulfonylureas) / octreotide
  • Thyroid drugs
  • Antithrombotics / vitamin K / protamine
  • Anesthetics - local / inhalational (2 chapt) / lipid emulsion
  • Chemotherapeutic agents(overview, miscellaneous, and methotrexate) / folinic acid, glucarpidase, intrathecal, extravasation,
  • Vitamins
  • Herbal preparation and Essential oils (2 chapt)
  • Food poisoning and botulism (2 chapt) / botulinum antitoxin
  • Arthropods / black widow and scorpion antivenom
  • Colchicine, podophyllin, and vinca alkaloids
  • Pharmaceutical additives
  • Dieting agents and regimens
  • Disulfiram and disulfiram-like reactions

Wednesday Conferences (3rd)

Wednesday Conferences

3rd Wednesday - Core Occupational / Environmental toxins (also 5th wed if there is one)
  • Semiconductor gases (GB 51; SK 33)
  • Plastics manufacture (SK 34, chart from GB 54)
  • Airbag manufacture (SK 36)
  • Dentistry (GB 9)
  • Asbestos
  • Hydrofluouric acid and fluourides / calcium antidote
  • Solvents (SK105,SK106)
  • Methemoglobin inducers / methylene blue
  • Marine envenomation
  • Dry cleaning industry (GB 11)
  • Mining / smelting industries (SK 40)
  • Performance enhancers (GF44)
  • Welders and Joiners (GB 38)
  • Simple asphyxiants and pulmonary irritants
  • Tire and rubber manufacture (SK 35)
  • PCBs and dioxin (Rom chapters)
  • Pulp and paper manufacture (SK 44)
  • Rodenticides (GF chapters: case study 9, Barium, SMFA, phosphorous, strychnine)
  • Petroleum / Crude oil industry (SK 67-69)
  • Pneumoconioses (SK41)berryliosis/ silicosis/organic dust/coal dust, silica
  • Absestos and MMFs (SK111 and 112)
  • Mutagenesis / carcinogenesis
  • Reproductive / developmental toxicology
  • Solvents and fuels
  • Cleansers and caustics
  • The indoor environment (GB 56)
  • Outdoor air pollution (GB 57)
  • Water pollution (GB 58)

Wednesday Conferences (4th)

Wednesday Conferences

4th Wednesday - Principles of Toxicology - chapters are chosen from Toxicologic Emergencies (Goldfrank LR, et al)
  • Neurologic principles
  • Ophthalmologic and Otolaryngologic principles
  • Thermoregulatory principles / dantrolene
  • Chemical principles
  • Dermatologic principles and transdermal toxicology
  • Respiratory principles
  • Gastrointestinal principles
  • Fluid, electrolyte, and acid-base principles
  • Hematologic principles
  • Principles and techniques applied to enhance elimination
  • Hepatic principles
  • Renal principles
  • Genitourinary principles
  • Chemical weapons
  • Biological weapons
  • Radiological principles / SKI / DTPA
  • Biochemical and metabolic principles
  • Reproductive and perinatal principle

Fellow Didactic Subjects

Fellow didactic subjects:

  • Veterinary products
  • Household products
  • Causal inference
  • Occupational assessment (biomonitoring, biomarkers, environmental sampling, PPE, pre-employment screening)
  • Risk communication and media training (chapt: risk assess. and risk comm)
  • Medicolegal / expert witness
  • Forensic Toxicology and Legal cases
  • Workplace drug testing and the role of an MRO
  • Building a medical toxicology CV
  • Chelation
  • Minor metals
  • Regulatory bodies
  • Reviewing for journals
  • Poison center administration and function (GF - poison prevention and education and poison centers and poison epidemiology)
  • Toxic alcohols (lesser known: DEG, EGBE)
  • Environmental toxins (WTC cough, multi-chemical sensitivities)
  • Miscellaneous drugs
  • Gastrointestinal drugs
  • Basic statistics (GF principes of epidemiology and research design)
  • Plants

Forensic Toxicology

Forensic Toxicology (3rd Thursdays): Topic (pre-reading chapter)

  • Introduction to pharmacokinetics (pharmacokinetic principles)
  • Post-mortem redistribution (post-mortem toxicology)
  • Legal ethanol (Ethanol / Thiamine / assessment of ethanol induced impairment)
  • Drug-facilitated sexual assault
  • Opioids
  • Illicit drugs - forensics

Curriculum