Superfund Basic Research Center
Neurotoxic Superfund Chemicals and Biomarkers
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Superfund Basic Research Program

The SBRC is funded by a grant (5 P42 ES010338) from the National Institute of Environmental Health Sciences (NIEHS) through its Superfund Basic Research Program.

Research Projects

The SBRC encompasses six research projects which investigate neurotoxic Superfund chemicals from a multidisciplinary perspective. Four biomedical projects address the detection and health impact of animal and human exposure to low concentrations of hazardous chemicals. Complementary non-biomedical research activities investigate chemical breakdown processes in groundwater. Finally, a community-based prevention project examines the neurobehavioral effects of Superfund chemical exposure on children.

Project A1: Assessment of VOC Exposure, by Route, in Populations Living Adjacent to Superfund Sites
Karla D. Thrall, PI
Battelle, Pacific Northwest National Laboratory

Project A2: Biomarkers of Neurotoxicant Exposure and Neurodegeneration
Mohammad I. Sabri, PI
Oregon Health & Science University

Project A3: Neurotoxic and Neuro-oncogenic Actions of Superfund Chemicals
Glen Kisby, PI
Oregon Health & Science University

Project A4: Hazardous Chemicals and Brain Developmental Plasticity
Christopher S. Wallace, PI
Oregon Health & Science University

Project B1: Microbial Transformation of Anaerobic Groundwater
Jennifer A. Field, PI
Oregon State University

Project C1: Assessing health effects: non-English-speaking children
Linda McCauley, PI
Oregon Health & Science University

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