BRUCE SCHNAPP: Overview

Bruce Schnapp grew up in Connecticut. He earned a BS with highest honors from the University of Connecticut, and a PhD, in Neuroscience, also at the University of Connecticut. After performing postdoctoral work in the Department of Neurobiology at Harvard Medical School and at the Institute of Neurology in London, England, Dr. Schnapp joined the NIH in 1983, but maintained his lab off the main NIH campus, at the Marine Biological Laboratory in Woods Hole, MA, to work with the squid giant axon. From 1983-1989, while at the MBL, Dr Schnapp, with a small group of collaborators, discovered cytoplasmic microtubule motors and their fundamental role in intracellular trafficking. Dr. Schnapp continued his work on molecular motors from 1989-91, as Associate Professor in the Department of Physiology at Boston University Medical School. In 1991, Dr. Schnapp moved his laboratory to Harvard Medical School in the Department of Cell and Molecular Physiology (later renamed Department of Cell Biology), where he remained until August 2001. In September, 2001, Dr. Schnapp assumes the position of Professor of Cell and Developmental Biology at Oregon Health and Sciences University, Portland, Oregon, where his laboratory will continue to investigate mechanisms of intracellular transport.


One of the attractions of a career in basic research is the freedom to define your own view of science. To me, and those in my lab, science is first and foremost, exploration. All of the hard work, frustration, and uncertainties of doing science are rewarded in those few occurrences in your career when you are truly on the edge of what is known, and you get the first glimpse of something broad, important, novel and, as it often happens, unexpected. Discoveries with these qualities usually occur in undeveloped, but otherwise extremely interesting areas, where few labs work and where the thinking is not very sophisticated. With this in mind, we have chosen to work on the dual problems of how motors organize intracellular traffic and how specific RNAs are localized. In science, as in other aspects of life, it helps to thing big, take chances, and keep looking ahead.