This movie shows that the otic and epibranchial placodes arise from a single group of precursors. By the end of the movie this single pax2a-positive domain separates into the otic (OV), facial (f) , and glossopharyngeal (g) and vagal (v) placodes. Confocal z-sections were taken every 6 min using pax2a:gfp transgenic line (generated in Michael Brand laboratory (Picker et al., 2002)).This is a side view with anterior is at left, movie begins at 11 hour post-fertilization and frames are taken at 200x magnification. Abbreviations: mhb-midbrain-hindbrain boundary; r3-rhombomere3; r5-rhombomere5; gVIII-accoustic ganglion.
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